OAS3
2'-5'-oligoadenylate synthase 3 is a protein in humans that is encoded by OAS3 gene. Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes preferentially dimers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L. Displays antiviral activity against Chikungunya virus (CHIKV), Dengue virus, Sindbis virus (SINV) and Semliki forest virus (SFV).
OAS3 Antibodies
OAS3 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA897591LA01HU | OAS3 Antibody | Human | ELISA, IHC, IF |
| CSB-PA897591LB01HU | OAS3 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA897591LC01HU | OAS3 Antibody, FITC conjugated | Human | |
| CSB-PA897591LD01HU | OAS3 Antibody, Biotin conjugated | Human | ELISA |
OAS3 Proteins
OAS3 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP897591HU CSB-EP897591HU CSB-BP897591HU CSB-MP897591HU CSB-EP897591HU-B |
Recombinant Human 2'-5'-oligoadenylate synthase 3 (OAS3), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
