AATF
AATF is a protein in humans that is encoded by AATF gene. May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle progression. Also antagonizes PAWR mediated induction of aberrant amyloid peptide production in Alzheimer disease (presenile and senile dementia), although the molecular basis for this phenomenon has not been described to date.
AATF Antibodies
AATF for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA05264A0Rb | AATF Antibody | Human | ELISA, IHC |
| CSB-PA001029GA01HU | AATF Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA970851 | AATF Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA001612 | AATF Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA031269 | AATF Antibody | Human,Mouse,Rat | ELISA,WB |
AATF Proteins
AATF Proteins for Gallus gallus (Chicken)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP716945CH CSB-EP716945CH CSB-BP716945CH CSB-MP716945CH CSB-EP716945CH-B |
Recombinant Chicken Protein AATF (AATF), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
AATF Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP865175HU CSB-EP865175HU CSB-BP865175HU CSB-MP865175HU CSB-EP865175HU-B |
Recombinant Human Protein AATF (AATF) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-RP052644h | Recombinant Human Protein AATF (AATF), partial | E.coli |
AATF Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP874132RA CSB-EP874132RA CSB-BP874132RA CSB-MP874132RA CSB-EP874132RA-B |
Recombinant Rat Protein AATF (Aatf) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
AATF Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP884948MO CSB-EP884948MO CSB-BP884948MO CSB-MP884948MO CSB-EP884948MO-B |
Recombinant Mouse Protein AATF (Aatf) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
AATF Proteins for Drosophila melanogaster (Fruit fly)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP893776DLU CSB-EP893776DLU CSB-BP893776DLU CSB-MP893776DLU CSB-EP893776DLU-B |
Recombinant Drosophila melanogaster Protein AATF-like (CG11188) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
