Recombinant Human Ras-related protein Rab-3B (RAB3B)

中文名稱：

人RAB3B重組蛋白
貨號：

CSB-YP019195HU
規格：
來源：

Yeast
其他：

中文名稱：

人RAB3B重組蛋白
貨號：

CSB-EP019195HU
規格：
來源：

E.coli
其他：

中文名稱：

人RAB3B重組蛋白
貨號：

CSB-EP019195HU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人RAB3B重組蛋白
貨號：

CSB-BP019195HU
規格：
來源：

Baculovirus
其他：

中文名稱：

人RAB3B重組蛋白
貨號：

CSB-MP019195HU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

RAB3B
Uniprot No.：

P20337
別名：

Brain antigen RAB3B; RAB3B; RAB3B member RAS oncogene family; RAB3B_HUMAN; ras related protein Rab 3B; Ras-related protein Rab-3B
種屬：

Homo sapiens (Human)
蛋白長度：

Full Length of Mature Protein
表達區域：

2-219
氨基酸序列

ASVTDGKTG VKDASDQNFD YMFKLLIIGN SSVGKTSFLF RYADDTFTPA FVSTVGIDFK VKTVYRHEKR VKLQIWDTAG QERYRTITTA YYRGAMGFIL MYDITNEESF NAVQDWATQI KTYSWDNAQV ILVGNKCDME EERVVPTEKG QLLAEQLGFD FFEASAKENI SVRQAFERLV DAICDKMSDS LDTDPSMLGS SKNTRLSDTP PLLQQNCSC
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Protein transport. Probably involved in vesicular traffic.
基因功能參考文獻：
1. Western blot experiments designed to detect flotillin 2, TMEM256, Rab3B and LAMTOR1 showed that the level of these proteins was higher in urinary exosomes from prostate cancer patients compared to healthy males PMID: 27664330
2. The structure of Rab3B:GDP complex was solved to 1.9A resolution and the structural base comparison with other Rab3 members provides a structural basis for the GDP/GTP switch in controlling the activity of small GTPase. PMID: 22321395
3. These results support an important inter-species difference in regulating insulin exocytosis where RAB3B is the most expressed isoform in human islets. PMID: 20807725
4. RAB3B improves dopamine handling and storage capacity at presynaptic terminals, and confers protection to vulnerable DA neurons. PMID: 20007772
5. these results add new information to the view that Rab3B is involved in the regulation of pituitary hormone secretion. PMID: 19384079
6. Rab3b/3c-positive recycling vesicles are involved in and may constitute one of the recycling compartments in exogenous antigen cross-presentation. PMID: 19717423
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亞細胞定位：

Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus.
蛋白家族：

Small GTPase superfamily, Rab family
數據庫鏈接：

HGNC: 9778

OMIM: 179510

KEGG: hsa:5865

STRING: 9606.ENSP00000360718

UniGene: Hs.123072