Recombinant Human Lengsin (LGSN)

中文名稱：

人LGSN重組蛋白
貨號：

CSB-YP729216HU
規格：
來源：

Yeast
其他：

中文名稱：

人LGSN重組蛋白
貨號：

CSB-EP729216HU
規格：
來源：

E.coli
其他：

中文名稱：

人LGSN重組蛋白
貨號：

CSB-EP729216HU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人LGSN重組蛋白
貨號：

CSB-BP729216HU
規格：
來源：

Baculovirus
其他：

中文名稱：

人LGSN重組蛋白
貨號：

CSB-MP729216HU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

LGSN
Uniprot No.：

Q5TDP6
別名：

LGSN; GLULD1; LGS; Lengsin; Glutamate-ammonia ligase domain-containing protein 1; Lens glutamine synthase-like
種屬：

Homo sapiens (Human)
蛋白長度：

full length protein
表達區域：

1-509
氨基酸序列

MNNEEDLLQE DSTRDEGNET EANSMNTLRR TRKKVTKPYV CSTEVGETDM SNSNDCMRDS SQILTPPQLS SRMKHIRQAM AKNRLQFVRF EATDLHGVSR SKTIPAHFFQ EKVSHGVCMP RGYLEVIPNP KDNEMNNIRA TCFNSDIVLM PELSTFRVLP WADRTARVIC DTFTVTGEPL LTSPRYIAKR QLSHLQASGF SLLSAFIYDF CIFGVPEILN SKIISFPALT FLNNHDQPFM QELVDGLYHT GANVESFSSS TRPGQMEISF LPEFGISSAD NAFTLRTGVK EVARKYNYIA SFFIETGFCD SGILSHSLWD VDRKKNMFCS TSGTEQLTIT GKKWLAGLLK HSAALSCLMA PSVSCRKRYS KDRKDLKKSV PTTWGYNDNS CIFNIKCHGE KGTRIENKLG SATANPYLVL AATVAAGLDG LHSSNEVLAG PDESTDFYQV EPSEIPLKLE DALVALEEDQ CLRQALGETF IRYFVAMKKY ELENEEIAAE RNKFLEYFI
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May act as a component of the cytoskeleton or as a chaperone for the reorganization of intermediate filament proteins during terminal differentiation in the lens. Does not seem to have enzymatic activity.
基因功能參考文獻：
1. In major depressive disorder genome-wide association study, best male-specific SNP was rs9362774 within LGSN gene PMID: 21621269
2. Lengsin belongs to the predominantly prokaryotic class 1 branch of glutamine synthetases but has lost enzyme activity PMID: 17161372
3. A potential chaperone-like role of Lengsin was investigated. PMID: 17010935
4. Novel spliced form of a lens protein as a novel lung cancer antigen, Lengsin splicing variant 4, is reported. PMID: 19459848
5. Lengsin is major novel protein of the vertebrate eye lens. PMID: 12107413
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蛋白家族：

Glutamine synthetase family
組織特異性：

Abundantly expressed in lens.
數據庫鏈接：

HGNC: 21016

OMIM: 611470

KEGG: hsa:51557

STRING: 9606.ENSP00000359691

UniGene: Hs.149585