TH
Th，全稱為Tamm-Horsfall蛋白（THP），是一種由腎臟髓袢升支及遠端小管曲部的上皮細胞合成分泌的糖蛋白。它也是尿液中含量最多的蛋白之一，常見別名包括T-H糖蛋白。在正常情況下，尿液中含有少量的THP，當尿THP排出減少時，可能與腎實質病變如慢性腎衰竭及急性腎小球腎炎等疾病有關，這些疾病會導致腎單位大量減少，從而使GFR顯著降低。相反，尿液THP含量增加則可能與間質性腎炎、尿路長期梗阻、自身免疫性藥物中毒、銅和鉻中毒等疾病引起的腎臟損傷有關，且其含量變化與病情相一致。此外，THP在尿道結石患者體外震波碎石治療中，其含量變化也可用于治療效果的判斷。在藥物研發方面，雖然已有國外研究者報道了腎結石大鼠腎臟組織THP表達的結果，但治療因素干預下腎結石大鼠腎臟組織表達的研究尚未見報道，這為解析腎結石發病機理提供了新的研究方向。
熱銷產品
TH Antibody (CSB-PA023470LA01HU)
驗證數據
Western Blot
Positive WB detected in: A549 whole cell lysate, Hela whole cell lysate, Rat brain tissue, Rat liver tissue, Mouse liver tissue, Mouse brain tissue
All lanes: TH antibody at 4μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 59, 56, 57, 46, 45 kDa
Observed band size: 59 kDa
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA023470LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA023470LA01HU at dilution of 1:100
Human tyrosine hydroxylase,TH ELISA Kit (CSB-E09661h)
驗證數據
貨號：CSB-E09661h
規格：96T/48T
靈敏度：0.078 ng/mL
檢測范圍：0.312 ng/mL-20 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
TH Antibodies
TH for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA154990 | Phospho-TH (Ser40) Antibody | Human,Mouse,Rat | ELISA,IF |
| CSB-PA439504 | Phospho-TH (Ser19) Antibody | Rat | ELISA,IF |
| CSB-PA695636 | TH (Ab-31) Antibody | Mouse,Rat | ELISA,WB |
| CSB-PA000731 | Phospho-TH (S19) Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA004284 | TH Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA004285 | TH Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA050254 | Phospho-TH (S62) Antibody | Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
| CSB-PA050255 | TH Antibody | Human,Mouse,Rat,Monkey | WB, IHC, ELISA |
| CSB-PA011030 | Phospho-TH (S71) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA195276 | TH Antibody | Human | ELISA,IHC |
| CSB-PA903853 | TH Antibody | Human | ELISA,IHC |
| CSB-PA023470LA01HU | TH Antibody | Human, Mouse, Rat | ELISA, WB, IHC |
| CSB-PA023470LB01HU | TH Antibody, HRP conjugated | Human | ELISA |
| CSB-PA023470LC01HU | TH Antibody, FITC conjugated | Human | |
| CSB-PA023470LD01HU | TH Antibody, Biotin conjugated | Human | ELISA |
TH for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA004286 | TH Antibody | Rat | WB, IHC, ELISA |
| CSB-PA006345 | Phospho-TH (S8) Antibody | Rat | WB, IHC, ELISA |
TH Proteins
TH Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP023470HU CSB-EP023470HU CSB-BP023470HU CSB-MP023470HU CSB-EP023470HU-B |
Recombinant Human Tyrosine 3-monooxygenase (TH) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TH ELISA Kit
TH ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E09661h | Human tyrosine hydroxylase,TH ELISA Kit | serum, plasma, tissue homogenates | 0.078 ng/mL |
