STK3
Serine/threonine-protein kinase 3 is a protein in humans that is encoded by STK3 gene. Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.
STK3 Antibodies
STK3 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA022843GA01HU | STK3 Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA614396ESR2HU | STK3 Antibody | Human, Mouse | ELISA, WB, IHC, IF |
| CSB-RA980100A0HU | STK3 Recombinant Monoclonal Antibody | Human | ELISA, WB |
STK3 Proteins
STK3 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP022843RA CSB-EP022843RA CSB-BP022843RA CSB-MP022843RA CSB-EP022843RA-B |
Recombinant Rat Serine/threonine-protein kinase 3 (Stk3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
STK3 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP614396HU CSB-EP614396HU CSB-BP614396HU CSB-MP614396HU CSB-EP614396HU-B |
Recombinant Human Serine/threonine-protein kinase 3 (STK3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
STK3 Proteins for Xenopus laevis (African clawed frog)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP743580XBE CSB-EP743580XBE CSB-BP743580XBE CSB-MP743580XBE CSB-EP743580XBE-B |
Recombinant Xenopus laevis Serine/threonine-protein kinase 3 (stk3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
STK3 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP767231DIL CSB-EP767231DIL CSB-BP767231DIL CSB-MP767231DIL CSB-EP767231DIL-B |
Recombinant Danio rerio Serine/threonine-protein kinase 3 (stk3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
STK3 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP881299MO CSB-EP881299MO CSB-BP881299MO CSB-MP881299MO CSB-EP881299MO-B |
Recombinant Mouse Serine/threonine-protein kinase 3 (Stk3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
