SORT1

SORT1，即分揀蛋白1，別名Sortilin、NT3、Gp95、NTR3、LDLCQ6，是一種跨膜蛋白，屬于VPS10相關(guān)sortilin蛋白家族。
SORT1在多個亞細(xì)胞區(qū)域發(fā)揮作用，包括高爾基體、內(nèi)體、內(nèi)質(zhì)網(wǎng)和細(xì)胞膜，主要功能是作為分選受體，參與蛋白質(zhì)的運輸和代謝。SORT1可通過各種途徑將蛋白質(zhì)從高爾基體運輸?shù)饺苊阁w和內(nèi)體，并且與多種蛋白質(zhì)的內(nèi)化和轉(zhuǎn)運相關(guān)。
SORT1的表達(dá)水平可能影響心肌梗死的風(fēng)險，并且與多種疾病相關(guān)，包括脂質(zhì)代謝疾病、某些類型的癌癥和神經(jīng)退行性疾病。 SORT1在調(diào)節(jié)膽固醇代謝、促進(jìn)神經(jīng)細(xì)胞凋亡以及可能影響胰島素響應(yīng)等方面具有重要的生物學(xué)意義。

熱銷產(chǎn)品

SORT1 Antibody (CSB-PA859102LA01HU)

驗證數(shù)據(jù)

IHC image of CSB-PA859102LA01HU diluted at 1:600 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

IHC image of CSB-PA859102LA01HU diluted at 1:600 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Human Sortilin(SORT1) ELISA kit (CSB-EL022412HU)

驗證數(shù)據(jù)

貨號：CSB-EL022412HU

規(guī)格：96T/48T

靈敏度：11.72 pg/mL

檢測范圍：46.88 pg/mL-3000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

SORT1 Antibody

SORT1 Protein

SORT1 ELISA Kit

SORT1 Antibodies

SORT1 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA022412GA01HU	SORT1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA448728	SORT1 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA194090	SORT1 Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA859102LA01HU	SORT1 Antibody	Human	ELISA, IHC
CSB-PA859102LB01HU	SORT1 Antibody, HRP conjugated	Human	ELISA
CSB-PA859102LC01HU	SORT1 Antibody, FITC conjugated	Human
CSB-PA859102LD01HU	SORT1 Antibody, Biotin conjugated	Human	ELISA

SORT1 for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA022412LA01RA	Sort1 Antibody	Rat	ELISA
CSB-PA022412LB01RA	Sort1 Antibody, HRP conjugated	Rat	ELISA

SORT1 Proteins

SORT1 Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP022412RA	Recombinant Rat Sortilin (Sort1), partial	Yeast
CSB-EP022412RA	Recombinant Rat Sortilin (Sort1), partial	E.coli
CSB-BP022412RA CSB-MP022412RA CSB-EP022412RA-B	Recombinant Rat Sortilin (Sort1), partial	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP022412RAa0	Recombinant Rat Sortilin (Sort1), partial	E.coli

SORT1 Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP740787MO CSB-EP740787MO CSB-BP740787MO CSB-MP740787MO CSB-EP740787MO-B	Recombinant Mouse Sortilin (Sort1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SORT1 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP761235DIL CSB-EP761235DIL CSB-BP761235DIL CSB-MP761235DIL CSB-EP761235DIL-B	Recombinant Danio rerio Sortilin (sort1), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

SORT1 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP859102HU CSB-EP859102HU CSB-BP859102HU CSB-EP859102HU-B	Recombinant Human Sortilin (SORT1), partial	Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli