RAD51B
Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. May promote the assembly of presynaptic RAD51 nucleoprotein filaments. Binds single-stranded DNA and double-stranded DNA and has DNA-dependent ATPase activity. Part of the RAD21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. The BCDX2 subcomplex RAD51B:RAD51C exhibits single-stranded DNA-dependent ATPase activity suggesting an involvement in early stages of the HR pathway.
RAD51B Antibodies
RAD51B for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA019267GA01HU | RAD51B Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA040144 | RAD51B Antibody | Human,Mouse,Monkey | WB, IHC, ELISA |
RAD51B Proteins
RAD51B Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP019267HU CSB-EP019267HU CSB-BP019267HU CSB-MP019267HU CSB-EP019267HU-B |
Recombinant Human DNA repair protein RAD51 homolog 2 (RAD51B) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RAD51B Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP019267MO CSB-EP019267MO CSB-BP019267MO CSB-MP019267MO CSB-EP019267MO-B |
Recombinant Mouse DNA repair protein RAD51 homolog 2 (Rad51b) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RAD51B Proteins for Arabidopsis thaliana (Mouse-ear cress)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP882886DOA CSB-EP882886DOA CSB-BP882886DOA CSB-MP882886DOA CSB-EP882886DOA-B |
Recombinant Arabidopsis thaliana DNA repair protein RAD51 homolog 2 (RAD51B) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RAD51B Proteins for Zea mays (Maize)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP894963ZAX CSB-EP894963ZAX CSB-BP894963ZAX CSB-MP894963ZAX CSB-EP894963ZAX-B |
Recombinant Zea mays DNA repair protein RAD51 homolog B (RAD51B) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
