PRLR
PRLR，即催乳素受體，是一種主要在垂體前葉以外的多種組織中表達的跨膜蛋白。催乳素受體通過與催乳素（PRL）結合，啟動細胞內的信號傳導過程，主要通過JAK2-STAT信號通路發揮作用，導致細胞核內特定基因的轉錄激活，從而影響細胞增殖、分化和功能。PRLR的信號轉導還涉及MAPK和PI3K/AKT等其他信號通路，這些通路在調節免疫反應、細胞生長和代謝等方面發揮作用。催乳素受體的生物學意義廣泛，它不僅在乳腺發育和泌乳中發揮關鍵作用，還參與調節生殖系統、免疫系統和神經系統的功能。PRLR的功能異常與多種疾病有關，包括某些類型的癌癥和生殖功能障礙。
熱銷產品
Recombinant Human Prolactin receptor (PRLR), partial (Active) (CSB-MP018727HU1d7)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human PRLR at 2 μg/ml can bind Anti-PRLR recombinant antibody (CSB-RA018727A0HU), the EC50 is 126.8-171.9 ng/mL.
The purity of PRLR was greater than 95% as determined by SEC-HPLC
PRLR Recombinant Monoclonal Antibody (CSB-RA018727A0HU)
驗證數據
The Binding Activity of Human PRLR with Anti-PRLR recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Human PRLR (CSB-MP018727HU1d7) at 2 μg/mL can bind Anti-PRLR recombinant antibody, the EC50 is 126.8-171.9 ng/mL.
The Binding Activity of Mouse Prlr with Anti-PRLR recombinant antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Mouse Prlr at 5 μg/mL (CSB-MP018727MO) can bind Anti-PRLR recombinant antibody, the EC50 is 4.021-8.706 ng/mL.
PRLR Antibodies
PRLR for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA964526 | PRLR Antibody | Human | ELISA,WB |
| CSB-PA018727LA01HU | PRLR Antibody | Human | ELISA, IHC |
| CSB-PA018727LB01HU | PRLR Antibody, HRP conjugated | Human | ELISA |
| CSB-PA018727LC01HU | PRLR Antibody, FITC conjugated | Human | |
| CSB-PA018727LD01HU | PRLR Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA018727A0HU | PRLR Recombinant Monoclonal Antibody | Human, Mouse | ELISA |
| CSB-RA018727MA1HU | PRLR (rolinsatamab) Recombinant Monoclonal Antibody | Human | ELISA, IHC |
PRLR Proteins
PRLR Proteins for Oryctolagus cuniculus (Rabbit)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018727RB1 CSB-EP018727RB1 CSB-BP018727RB1 CSB-MP018727RB1 CSB-EP018727RB1-B |
Recombinant Rabbit Prolactin receptor (PRLR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF018727RB | Recombinant Rabbit Prolactin receptor (PRLR) | in vitro E.coli expression system |
PRLR Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018727HU1 CSB-EP018727HU1 CSB-BP018727HU1 CSB-EP018727HU1-B |
Recombinant Human Prolactin receptor (PRLR), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-CF018727HU | Recombinant Human Prolactin receptor (PRLR) | in vitro E.coli expression system |
| CSB-MP018727HU1 | Recombinant Human Prolactin receptor (PRLR), partial | Mammalian cell |
| CSB-MP018727HU1d7 | Recombinant Human Prolactin receptor (PRLR), partial (Active) | Mammalian cell |
| CSB-MP018727HU | Recombinant Human Prolactin receptor (PRLR)-VLPs | Mammalian cell |
PRLR Proteins for Ovis aries (Sheep)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018727SH1 CSB-EP018727SH1 CSB-BP018727SH1 CSB-MP018727SH1 CSB-EP018727SH1-B |
Recombinant Sheep Prolactin receptor (PRLR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF018727SH | Recombinant Sheep Prolactin receptor (PRLR) | in vitro E.coli expression system |
PRLR Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018727RA1 CSB-EP018727RA1 CSB-BP018727RA1 CSB-MP018727RA1 CSB-EP018727RA1-B |
Recombinant Rat Prolactin receptor (Prlr), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF018727RA | Recombinant Rat Prolactin receptor (Prlr) | in vitro E.coli expression system |
PRLR Proteins for Sus scrofa (Pig)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018727PI CSB-EP018727PI CSB-BP018727PI CSB-MP018727PI CSB-EP018727PI-B |
Recombinant Pig Prolactin receptor (PRLR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRLR Proteins for Meleagris gallopavo (Common turkey)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018727MQV CSB-EP018727MQV CSB-BP018727MQV CSB-MP018727MQV CSB-EP018727MQV-B |
Recombinant Meleagris gallopavo Prolactin receptor (PRLR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRLR Proteins for Oreochromis niloticus (Nile tilapia) (Tilapia nilotica)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018727OET CSB-EP018727OET CSB-BP018727OET CSB-MP018727OET CSB-EP018727OET-B |
Recombinant Oreochromis niloticus Prolactin receptor (prlr), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRLR Proteins for Columba livia (Domestic pigeon)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018727DVK CSB-EP018727DVK CSB-BP018727DVK CSB-MP018727DVK CSB-EP018727DVK-B |
Recombinant Columba livia Prolactin receptor (PRLR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRLR Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018727MO CSB-EP018727MO CSB-BP018727MO CSB-EP018727MO-B |
Recombinant Mouse Prolactin receptor (Prlr), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-MP018727MO | Recombinant Mouse Prolactin receptor (Prlr), partial (Active) | Mammalian cell |
PRLR Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018727BO CSB-EP018727BO CSB-BP018727BO CSB-MP018727BO CSB-EP018727BO-B |
Recombinant Bovine Prolactin receptor (PRLR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRLR Proteins for Cervus elaphus (Red deer)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018727DRN CSB-EP018727DRN CSB-BP018727DRN CSB-MP018727DRN CSB-EP018727DRN-B |
Recombinant Cervus elaphus Prolactin receptor (PRLR), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
