PF4

PF4，全稱為血小板因子4，是一種存在于血小板α顆粒中的蛋白質，也被稱為血小板因子4或CXCL4。PF4在止血和血栓形成過程中發揮著重要作用，能夠抑制內皮細胞增殖、遷移和血管生成，調節細胞凋亡，擴大NK細胞炎癥應答等。PF4能夠與多種細胞表面的糖胺多糖結合，如肝素，從而發揮其生物學功能。此外，PF4還能降低正常造血干細胞對化療藥物的敏感性，而不影響腫瘤細胞對化療藥物的敏感性，其機制是PF4可逆性地抑制細胞增殖，將細胞阻止在S期，同時還保持細胞的生存力和活力。因此，PF4可作為造血細胞的防護劑用于腫瘤臨床治療中。近年來研究發現，血清PF4水平可作為胰腺癌病人存活和靜脈血栓栓塞形成的獨立指標，其開發具有很好的科研和臨床價值。目前，PF4的測定不僅作為體內高凝狀態的敏感指標，而且在多種疾患的診斷和預后的判斷中，PF4的測定也有相當重要的臨床意義。

熱銷產品

Human Platelet factor 4 variant(PF4V1) ELISA kit (CSB-EL017810HU)

驗證數據

貨號：CSB-EL017810HU

規格：96T/48T

靈敏度：0.156 ng/mL

檢測范圍：0.625 ng/mL-40 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

PF4 Antibody

PF4 Protein

PF4 ELISA Kit

PF4 Antibodies

PF4 for Homo sapiens (Human)

產品貨號	產品名稱	種屬反應性	應用類型
CSB-PA958757	PF4 Antibody	Human,Rat	IHC,ELISA
CSB-PA017809LA01HU	PF4 Antibody	Human	ELISA, IHC
CSB-PA017809LB01HU	PF4 Antibody, HRP conjugated	Human	ELISA
CSB-PA017809LC01HU	PF4 Antibody, FITC conjugated	Human
CSB-PA017809LD01HU	PF4 Antibody, Biotin conjugated	Human	ELISA

PF4 Proteins

PF4 Proteins for Oryctolagus cuniculus (Rabbit)

產品貨號	產品名稱	來源
CSB-YP017809RB CSB-EP017809RB CSB-BP017809RB CSB-MP017809RB CSB-EP017809RB-B	Recombinant Rabbit Platelet factor 4 (PF4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PF4 Proteins for Homo sapiens (Human)

產品貨號	產品名稱	來源
CSB-YP017810HU CSB-EP017810HU CSB-BP017810HU CSB-MP017810HU CSB-EP017810HU-B	Recombinant Human Platelet factor 4 variant (PF4V1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-BP017809HU CSB-MP017809HU CSB-EP017809HU-B	Recombinant Human Platelet factor 4 (PF4)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP000661HU	Recombinant Human Platelet factor 4 protein (PF4)	E.Coli

PF4 Proteins for Sus scrofa (Pig)

產品貨號	產品名稱	來源
CSB-BP017809PI CSB-MP017809PI CSB-EP017809PI-B	Recombinant Pig Platelet factor 4 (PF4)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PF4 Proteins for Ovis aries (Sheep)

產品貨號	產品名稱	來源
CSB-YP017809SH CSB-EP017809SH CSB-BP017809SH CSB-MP017809SH CSB-EP017809SH-B	Recombinant Sheep Platelet factor 4 (PF4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PF4 Proteins for Bos taurus (Bovine)

產品貨號	產品名稱	來源
CSB-YP017809BO CSB-EP017809BO CSB-BP017809BO CSB-MP017809BO CSB-EP017809BO-B	Recombinant Bovine Platelet factor 4 (PF4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PF4 Proteins for Rattus norvegicus (Rat)

產品貨號	產品名稱	來源
CSB-YP017809RA CSB-EP017809RA CSB-BP017809RA CSB-MP017809RA CSB-EP017809RA-B	Recombinant Rat Platelet factor 4 (Pf4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

PF4 Proteins for Mus musculus (Mouse)

產品貨號	產品名稱	來源
CSB-YP017809MO CSB-BP017809MO CSB-MP017809MO CSB-EP017809MO-B	Recombinant Mouse Platelet factor 4 (Pf4)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP001101MO	Recombinant Mouse Platelet factor 4 (Pf4)	E.Coli
CSB-EP017809MO	Recombinant mouse platelet factor 4 (Pf4)	E.coli

PF4 ELISA Kit

PF4 ELISA Kit for Homo sapiens (Human)

產品貨號	產品名稱	樣本類型	靈敏度
CSB-E07882h	Human Platelet Factor 4,PF-4 ELISA Kit	serum, plasma, tissue homogenates	1.56 ng/mL
CSB-EL017810HU	Human Platelet factor 4 variant(PF4V1) ELISA kit	serum, plasma, cell culture supernates, tissue homogenates	0.156 ng/mL