PDX1
PDX1，即胰十二指腸同源異形盒1，別名insulinpromoterfactor1、IPF1。它是一種同源盒轉錄因子，由人類第5號染色體上的PDX1基因編碼。PDX1在胰腺發育及β細胞功能維持中起重要調控作用。其作用機制包括結合到胰島素基因的啟動子上，單獨或協同其他因子調節胰島素的合成。PDX1對胰腺發育、β細胞成熟與分化、胰島素合成與分泌具有關鍵作用。PDX1基因的缺失或突變可導致胰腺發育不全和糖尿病的發生。PDX1在糖尿病治療中的研究具有重要的應用前景和潛在價值。
熱銷產品
驗證數據
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA068736(PDX1 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Hela cells, Jurkat cells, Primary antibody: CSB-PA068736(PDX1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
PDX1 Antibodies
PDX1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA017746GA01HU | PDX1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA011230 | PDX1 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA068736 | PDX1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA114989 | PDX1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
PDX1 Proteins
PDX1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP017746HU CSB-EP017746HU CSB-BP017746HU CSB-MP017746HU CSB-EP017746HU-B |
Recombinant Human Pancreas/duodenum homeobox protein 1 (PDX1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
