NR1I2
NR1I2，全稱為核受體亞家族1組I成員2，也被稱為PXR、NR1I2、Orphan nuclear receptor PAR1、Orphan nuclear receptor PXR、Pregnane X receptor、Steroid and xenobiotic receptor、SXR等。它是一種核受體，作為多功能轉(zhuǎn)錄因子，能夠被多種內(nèi)源性和外源性化合物激活。NR1I2在調(diào)節(jié)物質(zhì)代謝和分泌的基因中發(fā)揮關(guān)鍵作用，對(duì)利福平、金絲桃素、古古林、colupulone、異黃酮、孕烯醇酮和黃體酮等配體作出反應(yīng)。NR1I2的研究對(duì)于理解肝臟代謝和藥物代謝具有重要意義，其異常可能與多種疾病相關(guān)，如肝癌等。在藥物研發(fā)方面，NR1I2作為潛在的藥物靶點(diǎn)，其相關(guān)研究有助于開發(fā)新的治療策略。
熱銷產(chǎn)品
Recombinant Human Nuclear receptor subfamily 1 group I member 2 (NR1I2) (CSB-EP016048HU)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP016048HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) NR1I2.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP016048HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) NR1I2.
NR1I2 Antibody (CSB-PA016048ESR1HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA016048ESR1HU at dilution of 1:100
NR1I2 Antibodies
NR1I2 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA016048GA01HU | NR1I2 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA016048ESR1HU | NR1I2 Antibody | Human | ELISA, IHC |
| CSB-PA070162 | NR1I2 Antibody | Human | WB, ELISA |
NR1I2 Proteins
NR1I2 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP016048HU CSB-BP016048HU CSB-MP016048HU CSB-EP016048HU-B |
Recombinant Human Nuclear receptor subfamily 1 group I member 2 (NR1I2) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP016048HU | Recombinant Human Nuclear receptor subfamily 1 group I member 2 (NR1I2) | E.coli |
NR1I2 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP016048MO CSB-EP016048MO CSB-BP016048MO CSB-MP016048MO CSB-EP016048MO-B |
Recombinant Mouse Nuclear receptor subfamily 1 group I member 2 (Nr1i2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NR1I2 Proteins for Macaca mulatta (Rhesus macaque)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP848312MOW CSB-EP848312MOW CSB-BP848312MOW CSB-MP848312MOW CSB-EP848312MOW-B |
Recombinant Macaca mulatta Nuclear receptor subfamily 1 group I member 2 (NR1I2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
NR1I2 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP889932RA CSB-EP889932RA CSB-BP889932RA CSB-MP889932RA CSB-EP889932RA-B |
Recombinant Rat Nuclear receptor subfamily 1 group I member 2 (Nr1i2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
