MX1

MX1，全稱為Interferon-induced GTP-binding protein Mx1，是一種在細(xì)胞抗病毒應(yīng)答中發(fā)揮重要作用的蛋白。它也被稱為IFI-78K、interferon-inducible protein p78和MxA等。MX1蛋白主要由I型 и II型干擾素誘導(dǎo)產(chǎn)生，能夠抑制多種RNA和DNA病毒的復(fù)制過程。例如，它可以通過與病毒核衣殼結(jié)合并使其失活來抑制流感病毒和乙型肝炎病毒的復(fù)制。此外，MX1蛋白還能拮抗輪狀病毒和星狀病毒的復(fù)制。在流感病毒感染中，MX1蛋白能夠減少或延遲核衣殼蛋白（NP）的合成，并阻斷病毒粒子的內(nèi)吞途徑，從而抑制病毒的復(fù)制。MX1蛋白的相關(guān)疾病主要包括流感病毒感染和狂犬病等。目前，針對MX1蛋白的藥物研發(fā)主要集中在抗病毒藥物和免疫調(diào)節(jié)劑等方面。例如，一些研究正在探索MX1蛋白作為抗病毒藥物靶點的潛力，以及開發(fā)能夠增強MX1蛋白抗病毒活性的藥物。此外，還有一些研究正在探索MX1蛋白在自身免疫性疾病中的作用，以及開發(fā)針對這些疾病的MX1蛋白靶向藥物。

熱銷產(chǎn)品

MX1 Antibody (CSB-PA015249LA01HU)

驗證數(shù)據(jù)

Western Blot
Positive WB detected in: A549 whole cell lysate, NIH/3T3 whole cell lysate, Hela whole cell lysate
All lanes: MX1 antibody at 3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 76, 56 kDa
Observed band size: 76 kDa

Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA015249LA01HU at dilution of 1:100

Immunofluorescent analysis of Hela cells using CSB-PA015249LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Immunoprecipitating MX1 in Hela whole cell lysate
Lane 1: Rabbit control IgG instead of (1μg) instead of CSB-PA015249LA01HU in Hela whole cell lysate.For western blotting, a HRP-conjugated light chain specific antibody was used as the Secondary antibody (1/50000)
Lane 2: CSB-PA015249LA01HU (4μg) + Hela whole cell lysate (500μg)
Lane 3: Hela whole cell lysate (20μg)

Immunohistochemistry of paraffin-embedded human testicular tissue using CSB-PA015249LA01HU at dilution of 1:100

Human Interferon-induced GTP-binding protein Mx1(MX1) ELISA kit (CSB-EL015249HU)

驗證數(shù)據(jù)

貨號：CSB-EL015249HU

規(guī)格：96T/48T

靈敏度：3.9 pg/mL

檢測范圍：15.6 pg/mL-1000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

MX1 Antibody

MX1 Protein

MX1 ELISA Kit

MX1 Antibodies

MX1 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA015249GA01HU	MX1 Antibody	Human,Mouse	ELISA,WB,IHC
CSB-PA616832	MX1 Antibody	Human	ELISA,WB
CSB-PA015249LA01HU	MX1 Antibody	Human, Mouse	ELISA, WB, IHC, IF, IP
CSB-PA015249LB01HU	MX1 Antibody, HRP conjugated	Human	ELISA
CSB-PA015249LC01HU	MX1 Antibody, FITC conjugated	Human
CSB-PA015249LD01HU	MX1 Antibody, Biotin conjugated	Human	ELISA

MX1 Proteins

MX1 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP015249HU CSB-EP015249HU CSB-BP015249HU CSB-MP015249HU CSB-EP015249HU-B	Recombinant Human Interferon-induced GTP-binding protein Mx1 (MX1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli