MMP9
MMP9，即基質金屬蛋白酶9。它是一種在多種細胞類型中表達的酶，包括中性粒細胞、單核細胞、巨噬細胞等。MMP9的來源是人體細胞自身的基因編碼，其作用機制涉及催化細胞外基質(extracellular matrix, ECM)成分的降解，如膠原蛋白、彈性蛋白、明膠等，對維持組織結構和功能的動態平衡至關重要。MMP9的活性受到多種調控機制的影響，包括酶原激活、抑制因子如金屬蛋白酶組織抑制因子(TIMPs)的抑制作用 。MMP9在生物學上的意義非常廣泛，它參與了多種生理和病理過程，包括組織修復、炎癥反應、腫瘤發展和轉移等。MMP9通過降解ECM和非ECM底物，如細胞因子和生長因子，參與調節細胞增殖、遷移和凋亡等過程。在疾病狀態下，MMP9的異常表達或活性與心血管疾病、纖維化疾病、腫瘤侵襲和轉移等有關。例如，在心肌梗塞后的心臟重構中，MMP9的活性增加與心臟功能障礙相關 。MMP9的活性還與腫瘤微環境中的血管生成和免疫逃逸有關，使其成為癌癥治療的潛在靶點 。
熱銷產品
Recombinant Horse Matrix metalloproteinase-9 (MMP9), partial (CSB-YP3996HO)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
驗證數據
Western blot analysis of extracts from Hela cells using MMP-9 Antibody.
MMP9 Antibodies
MMP9 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA014679GA01HU | MMP9 Antibody | human | ELISA,WB,IHC |
| CSB-PA436677 | MMP9 Antibody | Human | ELISA,WB,IHC |
| CSB-PA142806 | MMP9 Antibody | Human | ELISA,WB,IHC |
| CSB-PA002676 | MMP9 Antibody | Human | WB, IHC, IF, ELISA |
| CSB-PA005569 | MMP9 Antibody | Human | WB, ELISA |
| CSB-PA699938 | MMP9 Antibody | Human | ELISA,IHC |
| CSB-PA255651 | MMP9 Antibody | Human | ELISA,IHC |
| CSB-PA563134 | MMP9 Antibody | Human | ELISA,IHC |
| CSB-PA151401 | MMP9 Antibody | Human | ELISA,WB,IHC |
| CSB-PA294107 | MMP9 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA796774 | MMP9 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-RA014679A0HU | MMP9 Recombinant Monoclonal Antibody | Human | ELISA, IHC, FC |
| CSB-RA014679MA1HU | MMP9 Recombinant Monoclonal Antibody | Human | ELISA, IHC |
MMP9 Proteins
MMP9 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP014679HU | Recombinant Human Matrix metalloproteinase-9 (MMP9), partial | Yeast |
| CSB-EP014679HU CSB-BP014679HU CSB-MP014679HU CSB-EP014679HU-B |
Recombinant Human Matrix metalloproteinase-9 (MMP9), partial | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MMP9 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP014679MO CSB-EP014679MO CSB-BP014679MO CSB-MP014679MO CSB-EP014679MO-B |
Recombinant Mouse Matrix metalloproteinase-9 (Mmp9) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MMP9 Proteins for Oryctolagus cuniculus (Rabbit)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP014679RB CSB-EP014679RB CSB-BP014679RB CSB-MP014679RB CSB-EP014679RB-B |
Recombinant Rabbit Matrix metalloproteinase-9 (MMP9), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MMP9 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-EP014679BO CSB-BP014679BO CSB-MP014679BO CSB-EP014679BO-B |
Recombinant Bovine Matrix metalloproteinase-9 (MMP9) | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MMP9 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP014679DO | Recombinant Dog Matrix metalloproteinase-9 (MMP9) | Yeast |
MMP9 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP014679RA CSB-EP014679RA CSB-BP014679RA CSB-MP014679RA CSB-EP014679RA-B |
Recombinant Rat Matrix metalloproteinase-9 (Mmp9) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MMP9 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-EP014679DO CSB-BP014679DO CSB-MP014679DO CSB-EP014679DO-B |
Recombinant Dog Matrix metalloproteinase-9 (MMP9) | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MMP9 ELISA Kit
MMP9 ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E13887c | Dog matrix metalloproteinase 9/Gelatinase B,MMP-9 ELISA Kit | serum, plasma | 3.12 ng/mL |
MMP9 ELISA Kit for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E08007m | Mouse matrix metalloproteinase 9/Gelatinase B,MMP-9 ELISA Kit | serum, plasma, tissue homogenates | 0.552 ng/mL |
MMP9 ELISA Kit for Oryctolagus cuniculus (Rabbit)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E06933Rb | Rabbit matrix metalloproteinase 9,MMP-9 ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 5.8 pg/mL |
MMP9 ELISA Kit for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E08008r | Rat matrix metalloproteinase 9/Gelatinase B,MMP-9 ELISA Kit | serum, plasma, tissue homogenates. | 0.195 ng/ml. |
MMP9 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E08006h | Human matrix metalloproteinase 9/Gelatinase B,MMP-9 ELISA Kit | serum, plasma, tissue homogenates, cell culture supernates, urine | 0.284 ng/mL |
