ITGA6
ITGA6，即整合素亞基α6，別名 Alpha6p、CD49f、VLA-6。它是一種細胞表面糖蛋白，由ITGA6基因編碼，屬于整合素家族的α亞基成員，在多種上皮細胞中表達。ITGA6與β4整合素鏈結合形成α6β4整合素，參與細胞與細胞外基質的粘附，特別是與層粘連蛋白的相互作用。其作用機制主要是通過介導細胞間的相互作用和信號傳導，參與細胞遷移、增殖和組織再生等過程。ITGA6在維持上皮完整性、調控免疫反應及傷口愈合中發揮重要作用。異常表達的ITGA6與某些疾病如交界性大皰性表皮松解癥、某些癌癥和纖維化疾病相關，是相關疾病研究和治療的潛在靶點。
熱銷產品
ITGA6 Recombinant Monoclonal Antibody (CSB-RA172768A0HU)
驗證數據
Immunofluorescence staining of MCF-7 cell with CSB-RA172768A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 536-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Overlay Peak curve showing Hela cells surface stained with CSB-RA172768A0HU (red line) at 1:100. The cells were incubated in 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1ug/1*106cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4℃.Control antibody (green line) was rabbit IgG (1ug/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.
ITGA6 Antibodies
ITGA6 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA011869GA01HU | ITGA6 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA000072 | Cleaved-ITGA6 (E942) Antibody | Human | WB, ELISA |
| CSB-PA006199 | ITGA6 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA079709 | ITGA6 Antibody | Human,Mouse | ELISA,IHC |
| CSB-PA011869LA01HU | ITGA6 Antibody | Human, Rat, Mouse | ELISA, WB, IF |
| CSB-PA011869LB01HU | ITGA6 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA011869LC01HU | ITGA6 Antibody, FITC conjugated | Human | |
| CSB-RA172768A0HU | ITGA6 Recombinant Monoclonal Antibody | Human | ELISA, IF, FC |
ITGA6 Proteins
ITGA6 Proteins for Gallus gallus (Chicken)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP011869CH CSB-EP011869CH CSB-BP011869CH CSB-MP011869CH CSB-EP011869CH-B |
Recombinant Chicken Integrin alpha-6 (ITGA6), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ITGA6 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP011869HU CSB-EP011869HU CSB-BP011869HU CSB-MP011869HU CSB-EP011869HU-B |
Recombinant Human Integrin alpha-6 (ITGA6), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ITGA6 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP720260MO CSB-EP720260MO CSB-BP720260MO CSB-MP720260MO CSB-EP720260MO-B |
Recombinant Mouse Integrin alpha-6 (Itga6), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
