IL1R2
IL1R2，全稱白細胞介素1受體2型，是一種重要的免疫調節蛋白，常見別名為IL-1R2或CD121b。該蛋白主要通過與白細胞介素1α、1β和1受體I型結合，發揮阻斷信號傳導的作用，從而抑制炎癥反應。IL1R2在多種細胞中表達，包括中性粒細胞、B細胞、單核細胞和巨噬細胞等，參與調節免疫應答和炎癥反應。IL1R2的表達上調與多種疾病相關，如腫瘤、自身免疫性疾病和炎癥性疾病等。近年來，IL1R2已成為藥物研發的重要靶點，已有多種針對IL1R2的抗體藥物進入臨床試驗階段，用于治療腫瘤和自身免疫性疾病。例如，抗IL1R2抗體可阻斷白細胞介素1的作用，從而減輕炎癥反應，改善疾病癥狀。此外，IL1R2也被用于腫瘤免疫治療，通過增強抗腫瘤免疫反應，提高腫瘤治療效果。IL1R2的研究和應用為相關疾病的治療提供了新的思路和方法。
熱銷產品
Recombinant Human Interleukin-1 receptor type 2 (IL1R2), partial (Active) (CSB-MP011622HU1)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA.Immobilized Human IL1B(CSB-MP011614HU) at 5 μg/ml can bind Human IL1R2. The EC50 is 89.65-100.5 ng/mL.
The purity of IL1R2 was greater than 90% as determined by SEC-HPLC
IL1R2 Antibody (CSB-PA011622ESR1HU)
驗證數據
Western blot
All lanes: Interleukin-1 receptor type 2 antibody at 3μg/ml + Mouse kidney tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 46, 34 kDa
Observed band size: 46 kDa
IL1R2 Antibodies
IL1R2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA011622ESR1HU | IL1R2 Antibody | Human, Mouse | ELISA, WB |
| CSB-PA005852 | IL1R2 Antibody | Human | WB, ELISA |
| CSB-PA247988 | IL1R2 Antibody | Human | ELISA,IHC |
IL1R2 Proteins
IL1R2 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP011622RA1 CSB-EP011622RA1 CSB-BP011622RA1 CSB-MP011622RA1 CSB-EP011622RA1-B |
Recombinant Rat Interleukin-1 receptor type 2 (Il1r2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF011622RA | Recombinant Rat Interleukin-1 receptor type 2 (Il1r2) | in vitro E.coli expression system |
IL1R2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP011622HU1 CSB-EP011622HU1 CSB-BP011622HU1 CSB-EP011622HU1-B |
Recombinant Human Interleukin-1 receptor type 2 (IL1R2), partial | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-CF011622HU | Recombinant Human Interleukin-1 receptor type 2 (IL1R2) | in vitro E.coli expression system |
| CSB-MP011622HU1 | Recombinant Human Interleukin-1 receptor type 2 (IL1R2), partial (Active) | Mammalian cell |
IL1R2 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP011622MO1 CSB-EP011622MO1 CSB-BP011622MO1 CSB-MP011622MO1 CSB-EP011622MO1-B |
Recombinant Mouse Interleukin-1 receptor type 2 (Il1r2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF011622MO | Recombinant Mouse Interleukin-1 receptor type 2 (Il1r2) | in vitro E.coli expression system |
IL1R2 Proteins for Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP644928DSU CSB-EP644928DSU CSB-BP644928DSU CSB-MP644928DSU CSB-EP644928DSU-B |
Recombinant Chlorocebus aethiops Interleukin-1 receptor type 2 (IL1R2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IL1R2 ELISA Kit
IL1R2 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04612h | Human soluble interleukin-1 receptor Ⅱ,IL-1sRⅡ ELISA kit | serum, plasma, tissue homogenates | 19.5 pg/mL |
