IGFBP1
IGFBP1，全稱為胰島素樣生長因子結(jié)合蛋白1，是一種重要的調(diào)節(jié)因子，可結(jié)合胰島素樣生長因子（IGFs）I和II，延長其半衰期并調(diào)節(jié)其活性。該蛋白常見別名包括IGFBP-1和胰島素樣生長因子結(jié)合蛋白1。IGFBP1在細(xì)胞培養(yǎng)中具有雙重調(diào)節(jié)影響，既能抑制也能刺激IGF的促生長作用，改變IGF與其受體的相互作用，從而微調(diào)信號通路。IGFBP1在多種生理和病理過程中發(fā)揮關(guān)鍵作用，如細(xì)胞遷移、腫瘤轉(zhuǎn)移和妊娠等。研究表明，IGFBP1的低水平與胰島素抵抗密切相關(guān)，是2型糖尿病風(fēng)險的一個預(yù)測因子。此外，IGFBP1還與子癇前期及胎兒生長受限等妊娠相關(guān)疾病有關(guān)。在藥物研發(fā)方面，IGFBP1已成為多種疾病治療的潛在靶點，包括自身免疫性疾病、心衰和癌癥等。例如，IGFBP1蛋白已被用于開發(fā)針對胃癌的預(yù)后因子和分子靶向治療。隨著研究的深入，IGFBP1在疾病診斷和治療中的應(yīng)用前景將更加廣闊。
熱銷產(chǎn)品
IGFBP1 Monoclonal Antibody (CSB-MA088331A0m)
驗證數(shù)據(jù)
All lanes: Mouse anti- Human Insulin-like growth factor-binding protein 1 monoclonal antibody at 1μg/ml
Lane 1:Pyrolysis liquid human placental tissue 7.5μg/ml
Lane 2:Pyrolysis liquid human placental tissue 3.25μg/ml
Lane 3:IGFBP1 transfected SF9 cell lysate
Lane 4:human amniotic fluid
Secondary Goat polyclonal to Mouse IgG at 1/5000 dilution
Predicted band size : 28kd
Observed band size : 35kd
Human insulin-like growth factors binding protein 1,IGFBP-1 ELISA Kit (CSB-E04586h)
驗證數(shù)據(jù)
貨號：CSB-E04586h
規(guī)格：96T/48T
靈敏度：0.39 ng/mL
檢測范圍：1.56 ng/mL-100 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
IGFBP1 Antibodies
IGFBP1 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA011095GA01HU | IGFBP1 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA08419B0Rb | IGFBP1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA08419A0Rb | IGFBP1 Antibody | Human | ELISA, WB, IHC |
| CSB-MA088331A0m | IGFBP1 Monoclonal Antibody | Human,Mouse | ELISA,WB |
| CSB-PA006134 | IGFBP1 Antibody | Human | WB, ELISA |
| CSB-PA009506 | IGFBP1 Antibody | Human | WB, IHC, ELISA |
| CSB-PA197609 | IGFBP1 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA032730 | IGFBP1 Antibody | Human | ELISA,IHC |
IGFBP1 Proteins
IGFBP1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP011095HU CSB-EP011095HU CSB-BP011095HU CSB-MP011095HU CSB-EP011095HU-B |
Recombinant Human Insulin-like growth factor-binding protein 1 (IGFBP1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IGFBP1 ELISA Kit
IGFBP1 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04586h | Human insulin-like growth factors binding protein 1,IGFBP-1 ELISA Kit | serum, plasma, tissue homogenates | 0.39 ng/mL |
