FOXA2
FOXA2，即叉頭框蛋白A2，別名HNF3B、TCF3B。FOXA2屬于叉頭類轉錄因子家族，具有高度保守的翼狀螺旋結構域，能夠以單體形式結合在靶基因啟動子區的DNA序列上。FOXA2通過與染色質的相互作用，改變染色質局部結構來調控基因表達，被稱為“先鋒因子”。FOXA2在多種生物學過程中起關鍵作用，包括胚胎發育、細胞分化及疾病發生過程。FOXA2還參與調節肝臟功能基因的表達，包括血漿蛋白、載脂蛋白、凝血因子以及葡萄糖、脂肪酸、氨基酸代謝中的關鍵代謝酶，參與肝臟發育、器官形成、代謝和穩態維持等多種生物學過程。FOXA2的表達異常與多種疾病相關，包括肝癌、肺癌、胰腺癌、胃癌、甲狀腺癌和大腸癌。
熱銷產品
驗證數據
Western blot analysis of extracts from 293, HT29, HepG2 cells using FoxA2(HNF3b) Antibody.
FOXA2 Antibodies
FOXA2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA146585 | FOXA2 Antibody | Human | ELISA,WB |
| CSB-PA927484 | FOXA2 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA167678 | FOXA2 Antibody | Human,Mouse,Rat | ELISA,WB |
FOXA2 Proteins
FOXA2 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP008795MO CSB-EP008795MO CSB-BP008795MO CSB-MP008795MO CSB-EP008795MO-B |
Recombinant Mouse Hepatocyte nuclear factor 3-beta (Foxa2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FOXA2 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP008795RA CSB-EP008795RA CSB-BP008795RA CSB-MP008795RA CSB-EP008795RA-B |
Recombinant Rat Hepatocyte nuclear factor 3-beta (Foxa2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FOXA2 Proteins for Oryzias latipes (Medaka fish) (Japanese ricefish)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP008795OFH CSB-EP008795OFH CSB-BP008795OFH CSB-MP008795OFH CSB-EP008795OFH-B |
Recombinant Oryzias latipes Hepatocyte nuclear factor 3-beta (foxa2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FOXA2 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP742473XBF CSB-EP742473XBF CSB-BP742473XBF CSB-MP742473XBF CSB-EP742473XBF-B |
Recombinant Xenopus tropicalis Forkhead box protein A2 (foxa2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FOXA2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP897462HU CSB-EP897462HU CSB-BP897462HU CSB-MP897462HU CSB-EP897462HU-B |
Recombinant Human Hepatocyte nuclear factor 3-beta (FOXA2) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
