CALCRL
CALCR，即降鈣素受體，別名Clr、Ct-r。它位于人類第19號(hào)染色體上，編碼的蛋白質(zhì)主要分布在內(nèi)質(zhì)網(wǎng)中，也存在于細(xì)胞核和細(xì)胞膜。CALCR的作用機(jī)制是通過(guò)與降鈣素結(jié)合，激活G蛋白偶聯(lián)受體信號(hào)通路，從而調(diào)節(jié)血鈣水平，抑制骨吸收，并增加腎臟對(duì)鈣的排泄。此外，CALCR在大腦中的表達(dá)表明它可能在中樞神經(jīng)系統(tǒng)中也有特定功能，如增強(qiáng)垂體前葉激素的分泌、抑制食欲和胃酸分泌，以及可能與痛覺調(diào)節(jié)或自閉癥的發(fā)病機(jī)制有關(guān)。CALCR在骨骼健康和骨疾病中扮演著重要角色，其基因突變與骨質(zhì)疏松癥有關(guān)，且在多種腫瘤中存在表達(dá)量的異常。
熱銷產(chǎn)品
CALCRL Antibody (CSB-PA788799)
驗(yàn)證數(shù)據(jù)
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA788799(CALCRL Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA788799(CALCRL Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human lung cancer tissue, Primary antibody: CSB-PA788799(CALCRL Antibody) at dilution 1/550, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds
CALCRL Antibodies
CALCRL for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA788799 | CALCRL Antibody | Human | ELISA,WB,IHC |
| CSB-PA079870 | CALCRL Antibody | Human | ELISA,WB |
CALCRL Proteins
CALCRL Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP004440BO1 CSB-EP004440BO1 CSB-BP004440BO1 CSB-MP004440BO1 CSB-EP004440BO1-B |
Recombinant Bovine Calcitonin gene-related peptide type 1 receptor (CALCRL), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF004440BO | Recombinant Bovine Calcitonin gene-related peptide type 1 receptor (CALCRL) | in vitro E.coli expression system |
CALCRL Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP608100XBF1 CSB-EP608100XBF1 CSB-BP608100XBF1 CSB-MP608100XBF1 CSB-EP608100XBF1-B |
Recombinant Xenopus tropicalis Calcitonin gene-related peptide type 1 receptor (calcrl), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF608100XBF | Recombinant Xenopus tropicalis Calcitonin gene-related peptide type 1 receptor (calcrl) | in vitro E.coli expression system |
CALCRL Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP614981HU1 CSB-EP614981HU1 CSB-BP614981HU1 CSB-MP614981HU1 CSB-EP614981HU1-B |
Recombinant Human Calcitonin gene-related peptide type 1 receptor (CALCRL), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF614981HU | Recombinant Human Calcitonin gene-related peptide type 1 receptor (CALCRL) | in vitro E.coli expression system |
CALCRL Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP730880RA1 CSB-EP730880RA1 CSB-BP730880RA1 CSB-MP730880RA1 CSB-EP730880RA1-B |
Recombinant Rat Calcitonin gene-related peptide type 1 receptor (Calcrl), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF730880RA | Recombinant Rat Calcitonin gene-related peptide type 1 receptor (Calcrl) | in vitro E.coli expression system |
CALCRL Proteins for Xenopus laevis (African clawed frog)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP767255XBE1 CSB-EP767255XBE1 CSB-BP767255XBE1 CSB-MP767255XBE1 CSB-EP767255XBE1-B |
Recombinant Xenopus laevis Calcitonin gene-related peptide type 1 receptor (calcrl), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF767255XBE | Recombinant Xenopus laevis Calcitonin gene-related peptide type 1 receptor (calcrl) | in vitro E.coli expression system |
CALCRL Proteins for Oncorhynchus gorbuscha (Pink salmon) (Salmo gorbuscha)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP805844OBF1 CSB-EP805844OBF1 CSB-BP805844OBF1 CSB-MP805844OBF1 CSB-EP805844OBF1-B |
Recombinant Oncorhynchus gorbuscha Calcitonin gene-related peptide type 1 receptor (calcrl), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF805844OBF | Recombinant Oncorhynchus gorbuscha Calcitonin gene-related peptide type 1 receptor (calcrl) | in vitro E.coli expression system |
CALCRL Proteins for Sus scrofa (Pig)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP848799PI1 CSB-EP848799PI1 CSB-BP848799PI1 CSB-MP848799PI1 CSB-EP848799PI1-B |
Recombinant Pig Calcitonin gene-related peptide type 1 receptor (CALCRL), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF848799PI | Recombinant Pig Calcitonin gene-related peptide type 1 receptor (CALCRL) | in vitro E.coli expression system |
CALCRL Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP865649MO1 CSB-EP865649MO1 CSB-BP865649MO1 CSB-MP865649MO1 CSB-EP865649MO1-B |
Recombinant Mouse Calcitonin gene-related peptide type 1 receptor (Calcrl), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF865649MO | Recombinant Mouse Calcitonin gene-related peptide type 1 receptor (Calcrl) | in vitro E.coli expression system |
CALCRL Proteins for Paralichthys olivaceus (Japanese flounder) (Hippoglossus olivaceus)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP872788ERT1 CSB-EP872788ERT1 CSB-BP872788ERT1 CSB-MP872788ERT1 CSB-EP872788ERT1-B |
Recombinant Paralichthys olivaceus Calcitonin gene-related peptide type 1 receptor (calcrl), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF872788ERT | Recombinant Paralichthys olivaceus Calcitonin gene-related peptide type 1 receptor (calcrl) | in vitro E.coli expression system |
