BRD7
Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at 'Tyr-216'. Down-regulates TRIM24-mediated activation of transcriptional activation by AR (By similarity). Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at 'Lys-9' (H3K9ac). Binds to the ESR1 promoter. Recruits BRCA1 and POU2F1 to the ESR1 promoter. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activation. Promotes acetylation of TP53 at 'Lys-382', and thereby promotes efficient recruitment of TP53 to target promoters. Inhibits cell cycle progression from G1 to S phase.
BRD7 Antibodies
BRD7 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA002803GA01HU | BRD7 Antibody | Human,Mouse | ELISA,WB |
| CSB-PA865097LA01HU | BRD7 Antibody | Human | ELISA, IHC, IF |
BRD7 Proteins
BRD7 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP002803MO CSB-EP002803MO CSB-BP002803MO CSB-MP002803MO CSB-EP002803MO-B |
Recombinant Mouse Bromodomain-containing protein 7 (Brd7) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BRD7 Proteins for Pongo abelii (Sumatran orangutan)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP722335PYX CSB-EP722335PYX CSB-BP722335PYX CSB-MP722335PYX CSB-EP722335PYX-B |
Recombinant Pongo abelii Bromodomain-containing protein 7 (BRD7), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BRD7 Proteins for Gallus gallus (Chicken)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP726518CH CSB-EP726518CH CSB-BP726518CH CSB-MP726518CH CSB-EP726518CH-B |
Recombinant Chicken Bromodomain-containing protein 7 (BRD7), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
BRD7 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP865097HU CSB-EP865097HU CSB-BP865097HU CSB-MP865097HU CSB-EP865097HU-B |
Recombinant Human Bromodomain-containing protein 7 (BRD7) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
