APOL1
APOL1，即載脂蛋白L1，別名APOL、APO-L、FSGS4、APOL-I，是一種由人類基因編碼的分泌型高密度脂蛋白（HDL）成分，主要在肝臟合成，也在其他多種組織中表達(dá)。
APOL1的作用機(jī)制涉及其在全身脂質(zhì)交換和運(yùn)輸中的功能，以及從外周細(xì)胞到肝臟的反向膽固醇轉(zhuǎn)運(yùn)。APOL1還能與載脂蛋白A-I結(jié)合，參與血漿中大部分膽固醇酯的形成，并促進(jìn)膽固醇從細(xì)胞中的流出。
APOL1具有保護(hù)人類免受非洲錐蟲感染的先天免疫功能，但某些APOL1基因變異與非糖尿病性腎病（如FSGS和HIVAN）的風(fēng)險(xiǎn)增加有關(guān)，這些變異在撒哈拉以南非洲和非洲散居人群中高度流行。APOL1的這些功能和變異對(duì)全球健康差異有顯著影響，尤其是在非洲血統(tǒng)人群中。
熱銷產(chǎn)品
APOL1 Recombinant Monoclonal Antibody (CSB-RA966671A0HU)
驗(yàn)證數(shù)據(jù)
Overlay Peak curve showing HepG2 cells stained with CSB-RA966671A0HU (red line) at 1:50. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1μg/1*106cells) for 45min at 4℃. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4℃.Control antibody (green line) was rabbit IgG (1μg/1*106cells) used under the same conditions. Acquisition of >10,000 events was performed.
Human Apolipoprotein L1(APOL1) ELISA kit (CSB-EL001940HU)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-EL001940HU
規(guī)格：96T/48T
靈敏度：1.95 ng/mL
檢測(cè)范圍：7.81 ng/mL-500 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
APOL1 Antibodies
APOL1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA001940GA01HU | APOL1 Antibody | Human | ELISA,WB,IHC |
| CSB-PA001940ESR1HU | APOL1 Antibody | Human | ELISA, IHC |
| CSB-PA001940ESR2HU | APOL1 Antibody | Human | ELISA, WB, IHC |
| CSB-PA923087 | APOL1 Antibody | Human | ELISA,WB |
| CSB-PA000906 | APOL1 Antibody | Human | WB, IHC, ELISA |
| CSB-PA082663 | APOL1 Antibody | Human | ELISA,WB,IHC |
| CSB-PA199459 | APOL1 Antibody | Human | ELISA,WB,IHC |
| CSB-RA966671A0HU | APOL1 Recombinant Monoclonal Antibody | Human | ELISA, FC |
APOL1 Proteins
APOL1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP001940HU CSB-EP001940HU CSB-BP001940HU CSB-MP001940HU CSB-EP001940HU-B |
Recombinant Human Apolipoprotein L1 (APOL1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
APOL1 ELISA Kit
APOL1 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL001940HU | Human Apolipoprotein L1(APOL1) ELISA kit | serum, plasma, cell culture supernates, tissue homogenates | 1.95 ng/mL |
