Recombinant Rat Syntaxin-2 (Stx2)

in vitro E.coli expression system

中文名稱：

大鼠Stx2重組蛋白
貨號：

CSB-CF022898RA
規格：
來源：

in vitro E.coli expression system
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

基因名：

Stx2
Uniprot No.：

P50279
別名：

Stx2; Epim; Syntaxin-2; Epimorphin
種屬：

Rattus norvegicus (Rat)
蛋白長度：

full length protein
表達區域：

1-290
氨基酸序列

MRDRLPDLTACRKSDDGDNAVIITVEKDHFMDAFFHQVEEIRSSIARIAQHVEDVKKNHSIILSAPNPEGKIKEELEDLNKEIKKTANRIRGKLKAIEQSCDQDENGNRTSVDLRIRRTQHSVLSRKFVDVMTEYNEAQILFRERSKGRIQRQLEITGRTTTDEELEEMLESGKPSIFISDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMVNNIERNVVNSVDYVEHAKEETKKAIKYQSKARRKKWIIAAVVVAVIAVLALIIGLTVGK
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
蛋白標簽：

N-terminal 10xHis-tagged
產品提供形式：

Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
緩沖液：

Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA：

Please contact us to get it.

產品評價

靶點詳情

功能：

Essential for epithelial morphogenesis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.
基因功能參考文獻：
1. miR-124a aggravates lipopolysaccharide-induced cardiac dysfunction and the miR-124a/STX2 pathway might serve as the potential diagnostic and therapeutic targets for septic cardiac dysfunction. PMID: 28560580
2. These data provide evidence for EPIM and SOX9 functioning by mutual negative feedback to regulate attributes of the quiescent or activated state of HSCs. PMID: 24971829
3. Epimorphin has morphogenetic effects on several epithelial tissues, including those of lung. PMID: 25119302
4. Epimorphin regulates bile duct formation of WB-F344 cells through effects on RhoA and C/EBPbeta, implicating a dual aspect of this morphoregulator in bile duct epithelial morphogenesis. PMID: 21935930
5. Epimorphin regulates bile duct formation via effects on mitosis orientation PMID: 20305811
6. expression in intestinal myofibroblasts induces epithelial morphogenesis PMID: 12464668
7. pIgA-R traffics through postendosomal rab3D-, rab11a-, and syntaxin 2-associated compartments, implicating these proteins in the regulation of transcytosis. PMID: 14578858
8. In conclusion, epimorphin is a factor that induces differentiation of hepatic stem-like cells through epithelial-mesenchymal cell contact. PMID: 14592430
9. anti-oxidative function of epimorphin is dramatic and is likely mediated by the activation of EGF receptors and the MEK/extracellular signal-regulated kinase and PI3 kinase/Akt signaling pathways PMID: 16891298
10. Epimorphin elicits hepatocyte spheroids by inducing proteases in rodent hepatocytes through NF-kappaB. PMID: 17935821
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亞細胞定位：

Membrane; Single-pass type IV membrane protein.
蛋白家族：

Syntaxin family
組織特異性：

Heart, spleen, liver, and testis.
數據庫鏈接：

KEGG: rno:25130

STRING: 10116.ENSRNOP00000001242

UniGene: Rn.10623