Recombinant Transcription factor unc-3 (unc-3)

中文名稱：

秀麗隱桿線蟲unc-3重組蛋白
貨號：

CSB-YP842372CXY
規格：
來源：

Yeast
其他：

中文名稱：

秀麗隱桿線蟲unc-3重組蛋白
貨號：

CSB-EP842372CXY
規格：
來源：

E.coli
其他：

中文名稱：

秀麗隱桿線蟲unc-3重組蛋白
貨號：

CSB-EP842372CXY-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

秀麗隱桿線蟲unc-3重組蛋白
貨號：

CSB-BP842372CXY
規格：
來源：

Baculovirus
其他：

中文名稱：

秀麗隱桿線蟲unc-3重組蛋白
貨號：

CSB-MP842372CXY
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

unc-3
Uniprot No.：

Q93705
別名：

unc-3; Y16B4A.1; Transcription factor unc-3; Uncoordinated protein 3; CEO/E
種屬：

Caenorhabditis elegans
蛋白長度：

full length protein
表達區域：

1-491
氨基酸序列

MSLTAPLRAG QMNFYDEPYN PVLNLHIQPS VKDENQRSTW PIIDTSNTST QIARAHFEKH PPNNLRKSNF FHFVIALYDR NSQPIEVERT QFAGFVEKEK EVDGQDTRNG IHYRLSLMFQ NGIRSEHDLF VRLIDSSTKQ AITYEGQDKN PEMCRVLLTH EVMCSRCCEK KSCGNRNETP SDPVIIDRFF LKFFLKCNQN CLKNAGNPRD MRRFQVVLCS SARIDGPLLA VSDNMFVHNN SKHGRRTKRT DASDDSEYSE SAELPSSVPV IKALFPSEGW IQGGTQVVLI GENFFEGLQV AFGTASPNWG ESVQLISPHA IRVTTPPKHS AGPVDVTLQY KSKTYSRGTP LRFSYITLAE PGIEYGFQRL QKLLPKYPGD PERLPKDQIL KRAAELAEAL YNRTSTESLS SYYHTQFDAT SDYAARTHTS PRSTLPYGAG PPALSSAVYQ TSYPTVNATP AANFLNTQTG FATFGAVNPF AATLQSSSRL S
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May play a role in the expression of proteins essential for axonal pathfinding and/or neuronal differentiation in both sensory and motor neurons. Cooperates with jmjd-3.1 and wdr-5.1 to ensure robust transdifferentiation of the Y rectal cell to the PDA motor neuron during larval development.
基因功能參考文獻：
1. Unc-3 is required for synaptogenesis.Synaptic input and output properties are temporally coordinated by Unc-3. PMID: 25913400
2. in addition to playing a role in neuronal terminal differentiation, UNC-3 is a cell lineage-specific regulator of apoptosis. PMID: 25790851
3. UNC-3 is a terminal selector for cholinergic motor neuron differentiation whose function is conserved across phylogeny. PMID: 22119902
4. UNC-3 is a critical component of the transcription factor code that integrates cell-intrinsic developmental programs with external signals to specify sensory neuronal identity PMID: 16143323
5. unc-3 represses a VC-like motor neuron program in the VA and VB motor neurons, which in wild-type animals control backwards and forwards locomotion, respectively. PMID: 18817768
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亞細胞定位：

Nucleus.
蛋白家族：

COE family
數據庫鏈接：

KEGG: cel:CELE_Y16B4A.1

STRING: 6239.Y16B4A.1.2

UniGene: Cel.5692