Recombinant Saccharomyces cerevisiae Ribosome-associated complex subunit SSZ1 (SSZ1), partial

中文名稱：

釀酒酵母SSZ1重組蛋白
貨號：

CSB-YP327890SVG
規格：
來源：

Yeast
其他：

中文名稱：

釀酒酵母SSZ1重組蛋白
貨號：

CSB-EP327890SVG
規格：
來源：

E.coli
其他：

中文名稱：

釀酒酵母SSZ1重組蛋白
貨號：

CSB-EP327890SVG-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

釀酒酵母SSZ1重組蛋白
貨號：

CSB-BP327890SVG
規格：
來源：

Baculovirus
其他：

中文名稱：

釀酒酵母SSZ1重組蛋白
貨號：

CSB-MP327890SVG
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

SSZ1
Uniprot No.：

P38788
別名：

SSZ1; PDR13; YHR064C; Ribosome-associated complex subunit SSZ1; DnaK-related protein SSZ1; Heat shock protein 70 homolog SSZ1; Pleiotropic drug resistance protein 13
種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Component of the ribosome-associated complex (RAC), a heterodimeric chaperone complex involved in regulation of accurate translation termination and in folding or maintaining nascent polypeptides in a folding-competent state. RAC stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones SSB1/SSB2 that bind to the nascent polypeptide chain. SSZ1 is required for ZUO1 to function efficiently as a J-protein for SSB1/SSB2. Also involved in pleiotropic drug resistance by post-translational activation of transcription factor PDR1.
基因功能參考文獻：
1. study presents structural analyses of the ribosome-associated complex (RAC) consisting (Hsp70) Ssz1 and the Hsp40 Zuo1; crystal structure of the Ssz1 ATPase domain bound to ATP-Mg(2) explains its catalytic inactivity and suggests Ssz1 may act before the RAC-associated chaperone Ssb PMID: 23202586
2. Ssz1 activates Pdr1 causing premature growth arrest of cells during the diauxic shift, through quorum sensing, as they adapt to the changing environmental conditions. PMID: 22203981
3. Ssz1 binds ATP, but none of the 11 different amino acid substitutions in the ATP-binding cleft affected Ssz1 function in vivo. PMID: 15908962
亞細胞定位：

Cytoplasm.
蛋白家族：

Heat shock protein 70 family
數據庫鏈接：

KEGG: sce:YHR064C

STRING: 4932.YHR064C