Recombinant Rat Insulin-like growth factor-binding protein 6 (Igfbp6)

中文名稱：

大鼠Igfbp6重組蛋白
貨號：

CSB-YP011100RA
規(guī)格：
來源：

Yeast
其他：

中文名稱：

大鼠Igfbp6重組蛋白
貨號：

CSB-EP011100RA
規(guī)格：
來源：

E.coli
其他：

中文名稱：

大鼠Igfbp6重組蛋白
貨號：

CSB-EP011100RA-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Igfbp6重組蛋白
貨號：

CSB-BP011100RA
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Igfbp6重組蛋白
貨號：

CSB-MP011100RA
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Igfbp6
Uniprot No.：

P35572
別名：

Igfbp6; Igfbp-6; Insulin-like growth factor-binding protein 6; IBP-6; IGF-binding protein 6; IGFBP-6
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Full Length of Mature Protein
表達區(qū)域：

26-226
氨基酸序列

ALAGC PGCGPGVQEE DAGSPADGCA ETGGCFRREG QPCGVYIPKC APGLQCQPRE NEETPLRALL IGQGRCQRAR GPSEETTKES KPHGGASRPR DRDRQKNPRT SAAPIRPSPV QDGEMGPCRR HLDSVLQQLQ TEVFRGGANG LYVPNCDLRG FYRKQQCRSS QGNRRGPCWC VDPMGQPLPV SPDGQGSSQC SARSSG
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Activates the MAPK signaling pathway and induces cell migration.
基因功能參考文獻：
1. IGFBP-6 was significantly up-regulated adjacent to the hematoma following intracerebral hemorrhage. PMID: 28044240
2. Following spinal cord injury, IGFBP6 was significantly up-regulated. PMID: 27888466
3. IGFBP6 has a role in binding to endothelial cells and in transendothelial transportation PMID: 12175646
4. IGFBP-6, a new negative effector of oligodendrocyte survival and differentiation, is expressed and localized to the Golgi complex in rat oligodendrocyte precursor (O2A) cells. PMID: 14515325
5. Toxic effect of TCDD on osteogenesis through altering Igfbp6 gene expression in osteoblasts is reported. PMID: 17978469
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亞細胞定位：

Secreted.
數(shù)據(jù)庫鏈接：

KEGG: rno:25641

STRING: 10116.ENSRNOP00000014807

UniGene: Rn.6431