Recombinant Rabbit Cytochrome P450 2E1 (CYP2E1)

中文名稱：

Recombinant Rabbit Cytochrome P450 2E1(CYP2E1)
貨號(hào)：

CSB-YP006425RB
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱：

Recombinant Rabbit Cytochrome P450 2E1(CYP2E1)
貨號(hào)：

CSB-EP006425RB
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱：

Recombinant Rabbit Cytochrome P450 2E1(CYP2E1)
貨號(hào)：

CSB-EP006425RB-B
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Rabbit Cytochrome P450 2E1(CYP2E1)
貨號(hào)：

CSB-BP006425RB
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱：

Recombinant Rabbit Cytochrome P450 2E1(CYP2E1)
貨號(hào)：

CSB-MP006425RB
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

CYP2E1
Uniprot No.：

P08682
別名：

CYP2E1; CYP2ECytochrome P450 2E1; EC 1.14.14.1; 4-nitrophenol 2-hydroxylase; EC 1.14.13.n7; CYPIIE1; Cytochrome P450 isozyme 3A; Cytochrome P450 LM3A; Cytochrome P450-ALC
種屬：

Oryctolagus cuniculus (Rabbit)
蛋白長(zhǎng)度：

Full Length of Mature Protein
表達(dá)區(qū)域：

2-493
氨基酸序列

AVLGITVAL LGWMVILLFI SVWKQIHSSW NLPPGPFPLP IIGNLLQLDL KDIPKSFGRL AERFGPVFTV YLGSRRVVVL HGYKAVREML LNHKNEFSGR GEIPAFREFK DKGIIFNNGP TWKDTRRFSL TTLRDYGMGK QGNEDRIQKE AHFLLEELRK TQGQPFDPTF VIGCTPFNVI AKILFNDRFD YKDKQALRLM SLFNENFYLL STPWLQVYNN FSNYLQYMPG SHRKVIKNVS EIKEYTLARV KEHHKSLDPS CPRDFIDSLL IEMEKDKHST EPLYTLENIA VTVADMFFAG TETTSTTLRY GLLILLKHPE IEEKLHEEID RVIGPSRMPS VRDRVQMPYM DAVVHEIQRF IDLVPSNLPH EATRDTTFQG YVIPKGTVVI PTLDSLLYDK QEFPDPEKFK PEHFLNEEGK FKYSDYFKPF SAGKRVCVGE GLARMELFLL LSAILQHFNL KPLVDPEDID LRNITVGFGR VPPRYKLCVI PRS
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics.
基因功能參考文獻(xiàn)：
1. The localization of CYP1A2, CYP2B4 and CYP2E1 within the ER was determined by partial membrane solubilization with Brij 98 PMID: 25236845
2. this study indicates that the gender difference in cytochrome P4503A activity may be one of the important factors for the development of steroid-induced osteonecrosis, possibly due to the effects of oestradiol. PMID: 24673874
亞細(xì)胞定位：

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. Mitochondrion inner membrane; Peripheral membrane protein.
蛋白家族：

Cytochrome P450 family
數(shù)據(jù)庫(kù)鏈接：

KEGG: ocu:100342572

STRING: 9986.ENSOCUP00000014766

UniGene: Ocu.1853