Recombinant Mouse TATA element modulatory factor (Tmf1), partial

中文名稱：

小鼠Tmf1重組蛋白
貨號：

CSB-YP023904MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Tmf1重組蛋白
貨號：

CSB-EP023904MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Tmf1重組蛋白
貨號：

CSB-EP023904MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Tmf1重組蛋白
貨號：

CSB-BP023904MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Tmf1重組蛋白
貨號：

CSB-MP023904MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Tmf1
Uniprot No.：

B9EKI3
別名：

Tmf1; Ara160; Gm153; TATA element modulatory factor; TMF; Androgen receptor coactivator 160 kDa protein; Androgen receptor-associated protein of 160 kDa
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Potential coactivator of the androgen receptor. May play critical roles in two RAB6-dependent retrograde transport processes: one from endosomes to the Golgi and the other from the Golgi to the ER. Mediates STAT3 degradation.
基因功能參考文獻：
1. The microtubule interacting domain (MIT) domain in TMF, along with microtubule integrity, are required for stable association of TMF with the Golgi apparatus. PMID: 26701263
2. Altered mucus secretion in TMF(-/-) mouse colons is accompanied by a reprogrammed intestinal microbiota, leading to a transmissible reduced sensitivity to induced colitis. PMID: 24639530
3. Data from knockout mice suggest that TMF/ARA160 participates in control of serum testosterone levels in males, and its absence results in major testicular and epididymal defects and abnormal spermatogenesis and Leydig cell proliferation. PMID: 23000399
4. absence of TMF/ARA160 renders the colonic mucus refractory to bacterial colonization and the large intestine less susceptible to the onset of colitis. PMID: 22553199
5. TMF/ARA160 is a key regulator which is essential for the onset of key events in the differentiation and maturation of mammalian sperm and whose absence severely compromises their ability to fertilize ova. PMID: 20691678
6. TMF/ARA160 is a BC-box-containing protein that mediates the degradation of Stat3 PMID: 15467733
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亞細胞定位：

Cytoplasm. Nucleus. Golgi apparatus membrane.
數據庫鏈接：

KEGG: mmu:232286

STRING: 10090.ENSMUSP00000093325

UniGene: Mm.30893