Recombinant Mouse Nck-associated protein 1 (Nckap1), partial

中文名稱：

小鼠Nckap1重組蛋白
貨號：

CSB-YP015532MO
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Nckap1重組蛋白
貨號：

CSB-EP015532MO
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Nckap1重組蛋白
貨號：

CSB-EP015532MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Nckap1重組蛋白
貨號：

CSB-BP015532MO
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Nckap1重組蛋白
貨號：

CSB-MP015532MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Nckap1
Uniprot No.：

P28660
別名：

Nckap1; Hem2; Kiaa0587; Nap1Nck-associated protein 1; NAP 1; Brain protein H19; MH19; Membrane-associated protein HEM-2; p125Nap1
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes.
基因功能參考文獻：
1. Nap1 is a constitutive and essential component of a WAVE2- and Abi-1-containing complex linking Rac to site-directed actin assembly. PMID: 14765121
2. Nap1 mutant phenotypes define the crucial roles of Nap1/WAVE-mediated actin regulation in tissue organization and establishment of the body plan of the mammalian embryo. PMID: 16831833
3. Inhibition of Nap1, a member of the WAVE actin-remodeling complex, results in accumulations of F-actin structures at the plasma membrane that are concomitant with a decrease in myoblast fusion. PMID: 19706686
亞細胞定位：

Cell membrane; Single-pass membrane protein; Cytoplasmic side. Cell projection, lamellipodium membrane; Single-pass membrane protein; Cytoplasmic side. Cytoplasm. Note=At the interface between the lamellipodial actin meshwork and the membrane.
蛋白家族：

HEM-1/HEM-2 family
組織特異性：

High expression in cerebral cortex, not in cerebellar cortex.
數據庫鏈接：

KEGG: mmu:50884

STRING: 10090.ENSMUSP00000028386

UniGene: Mm.25203