Recombinant Mouse KIF1-binding protein (Kbp)

中文名稱：

小鼠Kif1bp重組蛋白
貨號：

CSB-YP744404MO
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Kif1bp重組蛋白
貨號：

CSB-EP744404MO
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Kif1bp重組蛋白
貨號：

CSB-EP744404MO-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Kif1bp重組蛋白
貨號：

CSB-BP744404MO
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Kif1bp重組蛋白
貨號：

CSB-MP744404MO
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Kif1bp
Uniprot No.：

Q6ZPU9
別名：

Kifbp; Kbp; Kiaa1279; Kif1bp; KIF-binding protein; KIF1-binding protein
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-617
氨基酸序列

MANAPGPEIR EKFQAALALS RVELHKNPEK EPYKSKYGAR ALLEEVRALL GPAPEDEDEP AADDGPGDQA LGAGEPREAE GPGAQRALRL AVVEFHLGVN HIDTEELSAG EEHLVRCLSL LRPYRLSLGC VSLYIQAQNN LGILWSEREE IETARTYLES SEALYSQYMK EIGSPPLDPT EHFLPEEEKL TEQERSKRFE KVYTHNLYYL AQVYQHMEMF EKAAHYCHST LKRQLEHNAY HPMEWAINAA TLSQFYINKL CFMEARHCLS AANVIFGQTG KIPATEDTPE VEGDVPELYH QRKGEIARCW IKYCLTLMQN AQLSMQDNIG ELDLDKQSEL RALRKKELDE EESVRKRAVQ FGTGELCDAI SAVEEKVRYL RPLDFEEARE LFLLGQHYVC EAKEFFQIDG YVTDHIEVVQ DHSALFKVLS FFEADMERRC KMHKRRIAML EPLTVDLNPQ YYLLVSRQIQ FEIAHAYYDM MDLKVAIADK LRDPDSHIVK KINSLNKSAL KYYQLFLDSL RDPNKVFPEH IGEDVLRPAM LAKFRVARLY GKIITADPKK ELENLATSLE HYKFIVDYCE THPEAAQEIE VELELSKEMV SLLPTKMERF RAKMALT
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Required for neuronal development and differentiation. Required for organization of axonal microtubules, and axonal outgrowth and maintenance during peripheral and central nervous system development.
基因功能參考文獻：
1. TDH, responsible for mitochondrial production of acetyl-CoA in mouse embryonic stem cells, and the acetyltransferase GCN5L1 cooperate to acetylate Lys501 in KBP, allowing its recognition by and degradation via Fbxo15, an F-box protein transcriptionally controlled by the pluripotency core factors and repressed following differentiation. PMID: 28319092
2. KIF1-binding protein interacts with KIF3A in haploid male germ cells, promoting spermatid elongation. PMID: 26245936
3. KBP expression is up-regulated during neuronal development in mouse cortical neurons. PMID: 20621975
4. KBP is a new binding partner for KIF1Balpha that is a regulator of its transport function and thus represents a new type of kinesin interacting protein. PMID: 16225668
亞細胞定位：

Cytoplasm, cytoskeleton.
蛋白家族：

KIF1-binding protein family
組織特異性：

In th embryo it is expressed in cortical neurons; expression increases during neuronal development.
數據庫鏈接：

KEGG: mmu:72320

STRING: 10090.ENSMUSP00000065160

UniGene: Mm.258955