Recombinant Human Ribonucleoprotein PTB-binding 1 (RAVER1)

中文名稱：

人RAVER1重組蛋白
貨號：

CSB-YP814230HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人RAVER1重組蛋白
貨號：

CSB-EP814230HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人RAVER1重組蛋白
貨號：

CSB-EP814230HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人RAVER1重組蛋白
貨號：

CSB-BP814230HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人RAVER1重組蛋白
貨號：

CSB-MP814230HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

RAVER1
Uniprot No.：

Q8IY67
別名：

KIAA1978; Protein raver-1; RAVER1; RAVR1_HUMAN; Ribonucleoprotein PTB-binding 1; ribonucleoprotein, PTB binding 1
種屬：

Homo sapiens (Human)
蛋白長度：

Full Length of Mature Protein
表達區域：

2-606
氨基酸序列

AADVSVTHR PPLSPKSGAE VEAGDAAERR APEEELPPLD PEEIRKRLEH TERQFRNRRK ILIRGLPGDV TNQEVHDLLS DYELKYCFVD KYKGTAFVTL LNGEQAEAAI NAFHQSRLRE RELSVQLQPT DALLCVANLP PSLTQQQFEE LVRPFGSLER CFLVYSERTG QSKGYGFAEY MKKDSAARAK SDLLGKPLGP RTLYVHWTDA GQLTPALLHS RCLCVDRLPP GFNDVDALCR ALSAVHSPTF CQLACGQDGQ LKGFAVLEYE TAEMAEEAQQ QADGLSLGGS HLRVSFCAPG PPGRSMLAAL IAAQATALNR GKGLLPEPNI LQLLNNLGPS ASLQLLLNPL LHGSAGGKQG LLGAPPAMPL LNGPALSTAL LQLALQTQGQ KKPGILGDSP LGALQPGAQP ANPLLGELPA GGGLPPELPP RRGKPPPLLP SVLGPAGGDR EALGLGPPAA QLTPPPAPVG LRGSGLRGPL SHFYSGSPTS YFTSGLQAGL KQSHLSKAIG SSPLGSGEGL LGLSPGPNGH SHLLKVRAGG GDMQGWEAPA PQRPLTRPAL PSVSRPHWAA RNAALPTCCP RPSPAQKAAM WASTPRASAA TTRTPT
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping. Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA.
基因功能參考文獻：
1. These binding assays show that raver1 forms a ternary complex with metavinculin and vinculin mRNA. PMID: 22709580
2. Raver1 gene promoter region shares common features of ubiquitously expressed gene with the interacting splicing regulator PTB PMID: 17931803
3. RAVER1 interactions with vinculin and RNA suggest a feed forward pathway in directing messenger RNA to focal adhesions. PMID: 19523901
亞細胞定位：

Nucleus. Cytoplasm.
數據庫鏈接：

HGNC: 30296

OMIM: 609950

KEGG: hsa:125950

STRING: 9606.ENSP00000293677

UniGene: Hs.744952