Recombinant Human Neuron navigator 2 (NAV2), partial

中文名稱：

人NAV2重組蛋白
貨號：

CSB-YP015479HU
規格：
來源：

Yeast
其他：

中文名稱：

人NAV2重組蛋白
貨號：

CSB-EP015479HU
規格：
來源：

E.coli
其他：

中文名稱：

人NAV2重組蛋白
貨號：

CSB-EP015479HU-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人NAV2重組蛋白
貨號：

CSB-BP015479HU
規格：
來源：

Baculovirus
其他：

中文名稱：

人NAV2重組蛋白
貨號：

CSB-MP015479HU
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

NAV2
Uniprot No.：

Q8IVL1
別名：

NAV2; HELAD1; KIAA1419; POMFIL2; RAINB1; STEERIN2Neuron navigator 2; EC 3.6.4.12; Helicase APC down-regulated 1; Pore membrane and/or filament-interacting-like protein 2; Retinoic acid inducible in neuroblastoma 1; Steerin-2; Unc-53 homolog 2; unc53H2
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Possesses 3' to 5' helicase activity and exonuclease activity. Involved in neuronal development, specifically in the development of different sensory organs.
基因功能參考文獻：
1. NAV2 and CCND2 are novel candidate prognostic markers in uterine leiomyosarcoma and uterine low-grade endometrial stromal sarcoma, respectively. PMID: 28643014
2. The present study is the first study providing evidence of several genetic variants within the NAV2 gene influencing the risk and age at onset of Alzheimer's disease. PMID: 28778446
3. interaction between NAV2 and 14-3-3epsilon PMID: 24161943
4. regulated by all-trans retinoic acid in neuroblastoma cells PMID: 11904404
5. a novel gene, termed HELAD1 (helicase, APC down-regulated 1) plays important role in colorectal carcinogenesis (HELAD1) PMID: 12214280
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亞細胞定位：

Nucleus.
蛋白家族：

Nav/unc-53 family
組織特異性：

Highly expressed in the brain, kidney and liver. Also expressed in the thyroid, mammary gland, spinal cord, heart, placenta and lung. Abundantly expressed in colon cancers.
數據庫鏈接：

HGNC: 15997

OMIM: 607026

KEGG: hsa:89797

STRING: 9606.ENSP00000379394

UniGene: Hs.502116