Recombinant Human Myosin-1 (MYH1), partial

中文名稱：

人MYH1重組蛋白
貨號：

CSB-YP015289HU
說明書：

MSDS Datasheet
規格：
來源：

Yeast
其他：

中文名稱：

人MYH1重組蛋白
貨號：

CSB-EP015289HU
說明書：

MSDS Datasheet
規格：
來源：

E.coli
其他：

中文名稱：

人MYH1重組蛋白
貨號：

CSB-EP015289HU-B
說明書：

MSDS Datasheet
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人MYH1重組蛋白
貨號：

CSB-BP015289HU
說明書：

MSDS Datasheet
規格：
來源：

Baculovirus
其他：

中文名稱：

人MYH1重組蛋白
貨號：

CSB-MP015289HU
說明書：

MSDS Datasheet
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

MYH1
Uniprot No.：

P12882
別名：

adult 1; MYH1; MYH1_HUMAN; MyHC-2x; MyHC-IIx/d; Myosin heavy chain 1; Myosin heavy chain 2x; Myosin heavy chain; Myosin heavy chain IIx/d; Myosin-1; skeletal muscle
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Muscle contraction.
基因功能參考文獻：
1. Transcriptional levels of MHC-I, MHC-IIa, and MHC-IIb in denervation groups were significantly down-regulated compared with controls PMID: 26059207
2. Myosin isoforms impact single-fiber force generation and may lead to alterations in whole skeletal muscle performance. PMID: 25567808
3. adaptive response to reduced masticatory load was lower numerical and area proportion of MyHC-1 expressing fibres and higher numerical proportion of hybrid fibres in edentulous compared with dentate subjects PMID: 22489880
4. The human genioglossus muscle is composed of conventional myosin heavy chain isoforms and 3 primary myosin heavy chain phenotypes. PMID: 22337492
5. the expression levels of the MHC genes are associated with age and both PGC-1alpha and PGC-1beta and indicate that the MHC genes may to some extent be used to determine fibre-type composition in human skeletal muscle. PMID: 21470888
6. we found a higher percentage of fibers expressing fast MyHC IIx in tetraplegic cerebral palsy PMID: 17916367
7. Modular organization of phylogenetically conserved domains controlling developmental regulation of the human skeletal gene family PMID: 11971910
8. frequency of fibers expressing myosin heavy chain (MyHC) IIx increased in spastic paresis PMID: 17196619
9. Patients on hemodialysis demonstrate relatively fewer type 1 and consequently more type 2x fibres, with a corresponding change in MHC isoforms (MHC I and MHC IIX) in the skeletal muscle. PMID: 17853024
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亞細胞定位：

Cytoplasm, myofibril. Note=Thick filaments of the myofibrils.
蛋白家族：

TRAFAC class myosin-kinesin ATPase superfamily, Myosin family
數據庫鏈接：

HGNC: 7567

OMIM: 160730

KEGG: hsa:4619

STRING: 9606.ENSP00000226207

UniGene: Hs.689619