Recombinant Human Leukocyte-associated immunoglobulin-like receptor 2 (LAIR2)

中文名稱：

人LAIR2重組蛋白
貨號(hào)：

CSB-YP012722HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Yeast
其他：

中文名稱：

人LAIR2重組蛋白
貨號(hào)：

CSB-EP012722HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
其他：

中文名稱：

人LAIR2重組蛋白
貨號(hào)：

CSB-EP012722HU-B
說明書：

MSDS Datasheet
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人LAIR2重組蛋白
貨號(hào)：

CSB-BP012722HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

人LAIR2重組蛋白
貨號(hào)：

CSB-MP012722HU
說明書：

MSDS Datasheet
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
相關(guān)產(chǎn)品
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

LAIR2
Uniprot No.：

Q6ISS4
別名：

CD306; CD306 antigen; LAIR 2; LAIR-2; LAIR2; LAIR2_HUMAN; Leukocyte associated Ig like receptor 2; Leukocyte associated immunoglobulin like receptor 2; Leukocyte-associated immunoglobulin-like receptor 2; MGC71634; OTTHUMP00000068389; OTTHUMP00000068390
種屬：

Homo sapiens (Human)
蛋白長(zhǎng)度：

Full Length of Mature Protein
表達(dá)區(qū)域：

22-152
氨基酸序列

QEGALPRPS ISAEPGTVIS PGSHVTFMCR GPVGVQTFRL EREDRAKYKD SYNVFRLGPS ESEARFHIDS VSEGNAGLYR CLYYKPPGWS EHSDFLELLV KESSGGPDSP DTEPGSSAGT VPGTEASGFD AP
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

基因功能參考文獻(xiàn)：
1. recombinant LAIR-2-Fc inhibits complement-mediated lysis of cells sensitized with anti-HLA antibodies PMID: 24192271
2. the presence of high LAIR-2 levels in 74/80 sera from patients with autoimmune thyroid diseases PMID: 23691008
3. LAIR2-expressing extravillous trophoblasts associate with maternal spiral arterioles undergoing physiologic conversion PMID: 23332415
4. Two markers in two different genes (CNOT3 and LAIR2) showed significant association with ankylosing spondylitis. PMID: 22294640
5. LAIR-2/Fc has the capacity to interfere with platelet-collagen interactions mediated by Glycoprotein VI and the VWF/Glycoprotein Ib axis. PMID: 20730098
6. Human collagen II peptides II-17, -27, -30, -35, -38, -42, -49 & -56; and collagen III peptides III-1, 5, -8, -10, -12, -13, -22, -30, -38, -40, -44, -45, and -51 specifically interacted with hLAIR-2 expressed on K562 cells PMID: 19345263
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亞細(xì)胞定位：

Secreted.
數(shù)據(jù)庫鏈接：

HGNC: 6478

OMIM: 602993

KEGG: hsa:3904

STRING: 9606.ENSP00000301202

UniGene: Hs.43803