Recombinant Human Exocyst complex component 6B (EXOC6B), partial

中文名稱：

人EXOC6B重組蛋白
貨號：

CSB-YP007885HU
規(guī)格：
來源：

Yeast
其他：

中文名稱：

人EXOC6B重組蛋白
貨號：

CSB-EP007885HU
規(guī)格：
來源：

E.coli
其他：

中文名稱：

人EXOC6B重組蛋白
貨號：

CSB-EP007885HU-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

人EXOC6B重組蛋白
貨號：

CSB-BP007885HU
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

人EXOC6B重組蛋白
貨號：

CSB-MP007885HU
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

EXOC6B
Uniprot No.：

Q9Y2D4
別名：

EXOC6B; KIAA0919; SEC15B; SEC15L2; Exocyst complex component 6B; Exocyst complex component Sec15B; SEC15-like protein 2
種屬：

Homo sapiens (Human)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
基因功能參考文獻：
1. Homozygous nonsense variant in EXOC6B identified in two brothers with spondyloepimetaphyseal dysplasia and multiple joint dislocations syndrome. PMID: 26669664
2. EXOC6B and the exocyst complex might play an important role in the molecular pathogenesis of intellectual disability. PMID: 25256811
3. We report a 2p13.2 microdeletion in 2 subjects encompasing 2 genes, EXOC6B and CYP26B12 with clinical effects on cognitive function, and craniofacial and skeletal development. PMID: 23837398
4. Data suggest that the Rabin8-Rab8-Sec15 interaction may couple the activation of Rab8 to the recruitment of the Rab8 effector and is involved in the regulation of vesicular trafficking for primary cilium formation. PMID: 22433857
5. TNS3-EXOC6B and EXOC6B-TNS3 fusion transcripts are detected in a premature male newborn with a complex multisystemic phenotype associated with a balanced translocation. PMID: 18424204
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蛋白家族：

SEC15 family
數(shù)據(jù)庫鏈接：

HGNC: 17085

OMIM: 607880

KEGG: hsa:23233

STRING: 9606.ENSP00000272427

UniGene: Hs.303454