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中文名稱：CHRNG兔多克隆抗體
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貨號：CSB-PA005401ESR2HU
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規格：￥440
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圖片：
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Western blot
All lanes: CHRNG antibody at 5.5μg/ml
Lane 1: 293T whole cell lysate
Lane 2: HepG2 whole cell lysate
Lane 3: Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 58, 53 kDa
Observed band size: 58 kDa
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其他：
產品詳情
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產品名稱：Rabbit anti-Homo sapiens (Human) CHRNG Polyclonal antibody
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Uniprot No.：
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基因名：CHRNG
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別名：Acetylcholine receptor muscle gamma subunit antibody; Acetylcholine receptor protein gamma chain precursor antibody; Acetylcholine receptor subunit gamma antibody; ACHG antibody; ACHG_HUMAN antibody; Achr 3 antibody; AChR antibody; Achr3 antibody; ACHRG antibody; ACRG antibody; Cholinergic receptor nicotinic gamma antibody; Cholinergic receptor nicotinic gamma polypeptide antibody; CHRNG antibody; MGC133376 antibody
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宿主：Rabbit
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反應種屬：Human
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免疫原：Recombinant Human Acetylcholine receptor subunit gamma protein (328-517AA)
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免疫原種屬：Homo sapiens (Human)
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標記方式：Non-conjugated
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：Antigen Affinity Purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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產品提供形式：Liquid
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應用范圍：ELISA, WB
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推薦稀釋比：
Application Recommended Dilution WB 1:1000-1:5000 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
引用文獻
- The Fusion Protein MuSK‐Fc Functions as a Decoy to Block the Binding of Anti‐MuSK Antibodies to MuSK A Uzawa, H Akamine, M Yasuda,Scandinavian Journal of Immunology,2025
產品評價
相關產品
靶點詳情
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功能：After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
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基因功能參考文獻：
- CHRNG mutations associated with interfamilial variability of the severity of the Escobar variant of multiple pterygium syndrome PMID: 27245440
- Two siblings with Escobar syndrome caused by homozygous mutations of the CHRNG gene were identified. PMID: 25411939
- Rare cases of congenital arthrogryposis multiplex caused by novel recurrent CHRNG mutations. PMID: 25608830
- We did not identify a clear difference in mutation spectrum of the CHRNG gene between lethal form and non-lethal forms of multiple pterygium syndromes PMID: 22167768
- CHRNG mutations identified in families with Escobar syndrome show that the trait is a congenital dysmorphology caused by transient inactivation of the neuromuscular endplate. PMID: 16826520
- Mutations cxause lethal and nonlethal forms of multiple pterygium syndrome. PMID: 16826531
- constructed and characterized four AChR gamma extracellular domain variants PMID: 18502212
- This study suggests for the first time in humans, a possible role for genetic variation in the neuromuscular nicotinic acetylcholine receptor, particularly the gamma subunit, in systolic blood pressure regulation PMID: 18625075
- Detection of PAX3/7-FKHR fusion gene by one-step RT-PCR is useful in the diagnosis of rhabdomyosarcomas (RMS) and that AChR-gamma is overexpressed in Chinese RMS patients. PMID: 18988640
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相關疾病：Multiple pterygium syndrome, lethal type (LMPS); Multiple pterygium syndrome, Escobar variant (EVMPS)
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亞細胞定位：Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
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蛋白家族：Ligand-gated ion channel (TC 1.A.9) family, Acetylcholine receptor (TC 1.A.9.1) subfamily, Gamma/CHRNG sub-subfamily
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數據庫鏈接：
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