TAP1
Antigen peptide transporter 1 is a protein in humans that is encoded by TAP1 gene. Involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. Also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. Inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. Inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP1 and prevents the conformational rearrangement of TAP induced by peptide binding. Inhibited by human adenovirus E3-19K glycoprotein, which binds the TAP complex and acts as a tapasin inhibitor, preventing MHC class I/TAP association.
TAP1 Antibodies
TAP1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA023120GA01HU | TAP1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA023120ESR1HU | TAP1 Antibody | Human | ELISA, IHC |
TAP1 Proteins
TAP1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP023120HU CSB-EP023120HU CSB-BP023120HU CSB-MP023120HU CSB-EP023120HU-B |
Recombinant Human Antigen peptide transporter 1 (TAP1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TAP1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP023120MO CSB-EP023120MO CSB-BP023120MO CSB-MP023120MO CSB-EP023120MO-B |
Recombinant Mouse Antigen peptide transporter 1 (Tap1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TAP1 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP023120RA CSB-EP023120RA CSB-BP023120RA CSB-MP023120RA CSB-EP023120RA-B |
Recombinant Rat Antigen peptide transporter 1 (Tap1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TAP1 Proteins for Solanum lycopersicum (Tomato) (Lycopersicon esculentum)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP325320SZY CSB-EP325320SZY CSB-BP325320SZY CSB-MP325320SZY CSB-EP325320SZY-B |
Recombinant Solanum lycopersicum Suberization-associated anionic peroxidase 1 (TAP1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TAP1 Proteins for Gorilla gorilla gorilla (Lowland gorilla)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP631713GGZ CSB-EP631713GGZ CSB-BP631713GGZ CSB-MP631713GGZ CSB-EP631713GGZ-B |
Recombinant Gorilla gorilla gorilla Antigen peptide transporter 1 (TAP1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
