SERPINA5
SERPINA5，即絲氨酸蛋白酶抑制劑家族A成員5，是一種在人體血液中表達的蛋白質，由SERPINA5基因編碼。它是一種依賴肝素的絲氨酸蛋白酶抑制劑，主要在體液和分泌液中發揮作用。SERPINA5通過不可逆地結合到絲氨酸蛋白酶的活性位點，從而抑制這些酶的活性。它在血管內外的蛋白水解活動調節中扮演重要角色，參與血液凝固和炎癥反應，通過抑制抗凝因子活化蛋白C以及凝血因子，如凝血酶原、因子XI、因子Xa、血漿激肽釋放酶等，發揮止血和促進凝血的作用。在生物學意義上，SERPINA5的表達異常與多種疾病相關，包括血栓形成、癲癇、遺傳性球形紅細胞增多癥等，是血液系統和炎癥性疾病研究中的一個重要分子。
熱銷產品
Recombinant Mouse Plasma serine protease inhibitor (Serpina5) (CSB-BP021061MO)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
SERPINA5 Antibody (CSB-PA021061LA01HU)
驗證數據
Western Blot
Positive WB detected in: Rat liver tissue, Mouse liver tissue
All lanes: SERPINA5 antibody at 3μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 46 kDa
Observed band size: 46 kDa
Immunohistochemistry analysis of human ovarian cancer using CSB-PA021061LA01HU at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CSB-PA021061LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
SERPINA5 Antibodies
SERPINA5 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA021061GA01HU | SERPINA5 Antibody | Human | ELISA,WB,IHC |
| CSB-PA561778 | SERPINA5 Antibody | Human | ELISA,WB |
| CSB-PA003700 | SERPINA5 Antibody | Human | WB, IHC, ELISA |
| CSB-PA979705 | SERPINA5 Antibody | Human | ELISA,WB |
| CSB-PA729954 | SERPINA5 Antibody | Human | ELISA,WB,IHC |
| CSB-PA021061LA01HU | SERPINA5 Antibody | Human, Mouse, Rat | ELISA, WB, IHC, IF |
| CSB-PA021061LC01HU | SERPINA5 Antibody, FITC conjugated | Human | |
| CSB-PA021061LD01HU | SERPINA5 Antibody, Biotin conjugated | Human | ELISA |
SERPINA5 Proteins
SERPINA5 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP021061MO CSB-EP021061MO CSB-MP021061MO CSB-EP021061MO-B |
Recombinant Mouse Plasma serine protease inhibitor (Serpina5) | Yeast E.coli Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-BP021061MO | Recombinant Mouse Plasma serine protease inhibitor (Serpina5) | Baculovirus |
SERPINA5 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP021061HU CSB-EP021061HU CSB-BP021061HU CSB-MP021061HU CSB-EP021061HU-B |
Recombinant Human Plasma serine protease inhibitor (SERPINA5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SERPINA5 Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP868236BO CSB-EP868236BO CSB-BP868236BO CSB-MP868236BO CSB-EP868236BO-B |
Recombinant Bovine Plasma serine protease inhibitor (SERPINA5) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
SERPINA5 ELISA Kit
SERPINA5 ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-EL021061HU | Human Plasma serine protease inhibitor(SERPINA5) ELISA kit | serum, plasma, tissue homogenates, cell culture supernates, urine | 0.039 ng/mL |
