SELP
SELP，全稱為selectin P (granule membrane protein 140kDa, antigen CD62)，是一種存在于血小板α顆粒和內皮細胞Weibel-Palade小體中的跨膜糖蛋白。它也被稱為P-選擇素、GMP140、CD62P等。SELP蛋白在炎癥反應中發揮著重要作用，介導中性粒細胞和單核細胞與內皮細胞的初始粘附相互作用；在止血過程中，活化的血小板與中性粒細胞和單核細胞相互作用。SELP蛋白的表達和功能與多種疾病的發生發展密切相關，包括腎臟疾病、甲狀腺疾病、腫瘤等。近年來，研究發現SELP蛋白參與了多種腎臟疾病的病理生理過程，如腎缺血再灌注損傷、糖尿病腎病、慢性腎臟病及腎癌等。SELP蛋白的抗氧化活性可能在腎臟疾病的防治中發揮重要作用。此外，SELP蛋白的表達和功能也與甲狀腺疾病、腫瘤等密切相關。在藥物研發方面，針對SELP蛋白的抗體和重組蛋白等已被廣泛應用于基礎研究和臨床診斷中，并成為潛在的治療靶點。
熱銷產品
Recombinant Human P-selectin (SELP), partial (CSB-MP020978HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
SELP Antibody (CSB-PA020978LA01HU)
驗證數據
Immunofluorescence staining of HepG2 cells with CSB-PA020978LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Human P-Selectin ELISA kit (CSB-E04708h)
驗證數據
貨號：CSB-E04708h
規格：96T/48T
靈敏度：0.225 ng/mL
檢測范圍：0.9 ng/mL-60 ng/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
SELP Antibodies
SELP for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA006202 | SELP Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA020978LA01HU | SELP Antibody | Human | ELISA, IF |
| CSB-PA020978LB01HU | SELP Antibody, HRP conjugated | Human | ELISA |
| CSB-PA020978LC01HU | SELP Antibody, FITC conjugated | Human | |
| CSB-PA020978LD01HU | SELP Antibody, Biotin conjugated | Human | ELISA |
SELP Proteins
SELP Proteins for Ovis aries (Sheep)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP020978SH1 CSB-EP020978SH1 CSB-BP020978SH1 CSB-MP020978SH1 CSB-EP020978SH1-B |
Recombinant Sheep P-selectin (SELP), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF020978SH | Recombinant Sheep P-selectin (SELP) | in vitro E.coli expression system |
SELP Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP020978RA1 CSB-EP020978RA1 CSB-BP020978RA1 CSB-MP020978RA1 CSB-EP020978RA1-B |
Recombinant Rat P-selectin (Selp), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF020978RA | Recombinant Rat P-selectin (Selp) | in vitro E.coli expression system |
SELP Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP020978MO1 CSB-EP020978MO1 CSB-BP020978MO1 CSB-MP020978MO1 CSB-EP020978MO1-B |
Recombinant Mouse P-selectin (Selp), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF020978MO | Recombinant Mouse P-selectin (Selp) | in vitro E.coli expression system |
SELP Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP020978BO1 CSB-EP020978BO1 CSB-BP020978BO1 CSB-MP020978BO1 CSB-EP020978BO1-B |
Recombinant Bovine P-selectin (SELP), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF020978BO | Recombinant Bovine P-selectin (SELP) | in vitro E.coli expression system |
SELP Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-MP020978HU | Recombinant Human P-selectin (SELP), partial | Mammalian cell |
SELP ELISA Kit
SELP ELISA Kit for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04708h | Human P-Selectin ELISA kit | serum, plasma, tissue homogenates | 0.225 ng/mL |
SELP ELISA Kit for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E04709m | Mouse P-Selectin ELISA kit | serum, plasma, tissue homogenates | 7.8 pg/mL |
SELP ELISA Kit for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E07399r | Rat P-Selectin ELISA kit | serum, plasma, tissue homogenates | 2.34 ng/mL |
