RPS6KA1
Ribosomal protein S6 kinase alpha-1 is a protein in humans that is encoded by RPS6KA1 gene. Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of the transcription factors CREB1, ETV1/ER81 and NR4A1/NUR77, regulates translation through RPS6 and EIF4B phosphorylation, and mediates cellular proliferation, survival, and differentiation by modulating mTOR signaling and repressing pro-apoptotic function of BAD and DAPK1. In fibroblast, is required for EGF-stimulated phosphorylation of CREB1, which results in the subsequent transcriptional activation of several immediate-early genes. In response to mitogenic stimulation (EGF and PMA), phosphorylates and activates NR4A1/NUR77 and ETV1/ER81 transcription factors and the cofactor CREBBP.
RPS6KA1 Antibodies
RPS6KA1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA980342 | Phospho-RPS6KA1 (Thr348) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA212336 | Phospho-RPS6KA1 (Ser352) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA990220 | RPS6KA1 (Ab-348) Antibody | Human,Mouse,Rat | ELISA,WB,IF |
| CSB-PA906196 | RPS6KA1 (Ab-352) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA240123 | Phospho-RPS6KA1 (Thr573) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA698512 | RPS6KA1 (Ab-573) Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA004034 | RPS6KA1 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA040251 | Phospho-RPS6KA1 (S380) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA040252 | Phospho-RPS6KA1 (T359/S363) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA040253 | Phospho-RPS6KA1 (T573) Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA040254 | RPS6KA1 Antibody | Human,Mouse,Rat | WB, IHC, IF, ELISA |
| CSB-PA121989 | RPS6KA1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA798266 | RPS6KA1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA618984LA01HU | RPS6KA1 Antibody | Human | ELISA, IF |
| CSB-PA618984LB01HU | RPS6KA1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA618984LC01HU | RPS6KA1 Antibody, FITC conjugated | Human | |
| CSB-PA618984LD01HU | RPS6KA1 Antibody, Biotin conjugated | Human | ELISA |
| CSB-RA618984A359phHU | Phospho-RPS6KA1 (T359+S363) Recombinant Monoclonal Antibody | Human | ELISA, WB, IF, IP |
| CSB-RA618984A380phHU | Phospho-RPS6KA1 (S380) Recombinant Monoclonal Antibody | Human | ELISA, WB, IP |
RPS6KA1 Proteins
RPS6KA1 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP020464MO CSB-EP020464MO CSB-BP020464MO CSB-MP020464MO CSB-EP020464MO-B |
Recombinant Mouse Ribosomal protein S6 kinase alpha-1 (Rps6ka1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RPS6KA1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP618984HU CSB-EP618984HU CSB-BP618984HU CSB-MP618984HU CSB-EP618984HU-B |
Recombinant Human Ribosomal protein S6 kinase alpha-1 (RPS6KA1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RPS6KA1 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP730906RA CSB-EP730906RA CSB-BP730906RA CSB-MP730906RA CSB-EP730906RA-B |
Recombinant Rat Ribosomal protein S6 kinase alpha-1 (Rps6ka1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
