RAB7B
Ras-related protein Rab-7bis a protein in humans that is encoded by RAB7B gene. Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway.
RAB7B Antibodies
RAB7B for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA019220GA01HU | RAB7B Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA019220LA01HU | RAB7B Antibody | Human | ELISA, IF |
| CSB-PA019220LB01HU | RAB7B Antibody, HRP conjugated | Human | ELISA |
| CSB-PA019220LC01HU | RAB7B Antibody, FITC conjugated | Human |
RAB7B Proteins
RAB7B Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP600945BO CSB-EP600945BO CSB-BP600945BO CSB-MP600945BO CSB-EP600945BO-B |
Recombinant Bovine Ras-related protein Rab-7b (RAB7B) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RAB7B Proteins for Dictyostelium discoideum (Slime mold)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP700778DKK CSB-EP700778DKK CSB-BP700778DKK CSB-MP700778DKK CSB-EP700778DKK-B |
Recombinant Dictyostelium discoideum Ras-related protein Rab-7B (rab7B) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RAB7B Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP845015MO CSB-EP845015MO CSB-BP845015MO CSB-MP845015MO CSB-EP845015MO-B |
Recombinant Mouse Ras-related protein Rab-7b (Rab7b) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
RAB7B Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP853383HU CSB-EP853383HU CSB-BP853383HU CSB-MP853383HU CSB-EP853383HU-B |
Recombinant Human Ras-related protein Rab-7b (RAB7B) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
