PROK1

PROK1，全名為Prokineticin-1，常見別名包括EG-VEGF、PK1、PRK1等。該蛋白主要由內(nèi)分泌腺（如卵巢、睪丸、腎上腺和胎盤）表達，參與血管內(nèi)皮細胞的增殖、遷移和窗孔形成。PROK1蛋白在低氧條件下表達增強，并與血管內(nèi)皮生長因子（VEGF）的表達互補，提示兩者可能協(xié)同作用。近年來，PROK1蛋白在多種疾病中的潛在作用引起關(guān)注，包括心血管疾病、腫瘤和自身免疫性疾病等。針對PROK1蛋白的藥物研發(fā)正在積極進行中，部分創(chuàng)新藥物已進入臨床試驗階段，顯示出良好的治療效果和安全性。例如，一些靶向PROK1蛋白的單克隆抗體藥物被用于治療心血管疾病和腫瘤，而小分子抑制劑則被開發(fā)用于調(diào)節(jié)PROK1蛋白的表達和活性。隨著對PROK1蛋白研究的深入，未來有望開發(fā)出更多針對該蛋白的創(chuàng)新藥物，為相關(guān)疾病的治療提供新的選擇。

熱銷產(chǎn)品

PROK1 Antibody (CSB-PA018746LA01HU)

驗證數(shù)據(jù)

IHC image of CSB-PA018746LA01HU diluted at 1:200 and staining in paraffin-embedded human placenta tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

IHC image of CSB-PA018746LA01HU diluted at 1:200 and staining in paraffin-embedded human adrenal gland tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

Human prokineticin 1(PROK1/EG-VEGF) ELISA kit (CSB-E04532h)

驗證數(shù)據(jù)

貨號：CSB-E04532h

規(guī)格：96T/48T

靈敏度：0.078 ng/mL

檢測范圍：0.312 ng/mL-20 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

PROK1 Antibody

PROK1 Protein

PROK1 ELISA Kit

PROK1 Antibodies

PROK1 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA018746LA01HU	PROK1 Antibody	Human	ELISA, IHC
CSB-PA018746LB01HU	PROK1 Antibody, HRP conjugated	Human	ELISA
CSB-PA018746LC01HU	PROK1 Antibody, FITC conjugated	Human
CSB-PA018746LD01HU	PROK1 Antibody, Biotin conjugated	Human	ELISA

PROK1 Proteins

PROK1 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP018746HU CSB-EP018746HU CSB-BP018746HU CSB-MP018746HU CSB-EP018746HU-B	Recombinant Human Prokineticin-1 (PROK1)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-AP002671HU	Recombinant Human Prokineticin-1 protein (PROK1)	E.Coli