PRKG1
cGMP-dependent protein kinase 1 is a protein in humans that is encoded by PRKG1 gene. Serine/threonine protein kinase that acts as key mediator of the nitric oxide (NO)/cGMP signaling pathway. GMP binding activates PRKG1, which phosphorylates serines and threonines on many cellular proteins. Numerous protein targets for PRKG1 phosphorylation are implicated in modulating cellular calcium, but the contribution of each of these targets may vary substantially among cell types. Proteins that are phosphorylated by PRKG1 regulate platelet activation and adhesion, smooth muscle contraction, cardiac function, gene expression, feedback of the NO-signaling pathway, and other processes involved in several aspects of the CNS like axon guidance, hippocampal and cerebellar learning, circadian rhythm and nociception. Smooth muscle relaxation is mediated through lowering of intracellular free calcium, by desensitization of contractile proteins to calcium, and by decrease in the contractile state of smooth muscle or in platelet activation. Regulates intracellular calcium levels via several pathways.
PRKG1 Antibodies
PRKG1 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA619797ESR2HU | PRKG1 Antibody | Human, Mouse | ELISA, WB |
PRKG1 Proteins
PRKG1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP018715MO CSB-BP018715MO CSB-MP018715MO CSB-EP018715MO-B |
Recombinant Mouse cGMP-dependent protein kinase 1 (Prkg1) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRKG1 Proteins for Bos taurus (Bovine)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP018715BO CSB-EP018715BO CSB-BP018715BO CSB-MP018715BO CSB-EP018715BO-B |
Recombinant Bovine cGMP-dependent protein kinase 1 (PRKG1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRKG1 Proteins for Oryctolagus cuniculus (Rabbit)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP018715RB CSB-EP018715RB CSB-BP018715RB CSB-MP018715RB CSB-EP018715RB-B |
Recombinant Rabbit cGMP-dependent protein kinase 1 (PRKG1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRKG1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP619797HU CSB-EP619797HU CSB-BP619797HU CSB-MP619797HU CSB-EP619797HU-B |
Recombinant Human cGMP-dependent protein kinase 1 (PRKG1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
