PRKCB
Protein kinase C beta type is a protein in humans that is encoded by PRKCB gene. Calcium-activated, phospholipid and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation. Mediates the activation of the canonical NF-kappa-B pathway (NFKB1) by direct phosphorylation of CARD11/CARMA1 at 'Ser-559', 'Ser-644' and 'Ser-652'. Phosphorylation induces CARD11/CARMA1 association with lipid rafts and recruitment of the BCL10-MALT1 complex as well as MAP3K7/TAK1, which then activates IKK complex, resulting in nuclear translocation and activation of NFKB1.
PRKCB Antibodies
PRKCB for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA018700GA01HU | PRKCB Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA206081 | Phospho-PRKCB (Thr641) Antibody | Human,Mouse,Rat | ELISA,WB,IHC,IF |
| CSB-PA067031 | Phospho-PRKCB (Ser661) Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA030241 | Phospho-PRKCB (S661) Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA030242 | PRKCB Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA095590 | PRKCB Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA144857 | PRKCB Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA15849A0Rb | PRKCB Antibody | Human, Rat | ELISA, WB, IHC, IF |
| CSB-PA15849B0Rb | PRKCB Antibody, HRP conjugated | Human | ELISA |
| CSB-PA15849C0Rb | PRKCB Antibody, FITC conjugated | Human | |
| CSB-PA15849D0Rb | PRKCB Antibody, Biotin conjugated | Human | ELISA |
PRKCB Proteins
PRKCB Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018700MO CSB-EP018700MO CSB-BP018700MO CSB-MP018700MO CSB-EP018700MO-B |
Recombinant Mouse Protein kinase C beta type (Prkcb) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRKCB Proteins for Oryctolagus cuniculus (Rabbit)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018700RB CSB-EP018700RB CSB-BP018700RB CSB-MP018700RB CSB-EP018700RB-B |
Recombinant Rabbit Protein kinase C beta type (PRKCB), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRKCB Proteins for Bos taurus (Bovine)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018700BO CSB-EP018700BO CSB-BP018700BO CSB-MP018700BO CSB-EP018700BO-B |
Recombinant Bovine Protein kinase C beta type (PRKCB), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRKCB Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018700HU CSB-EP018700HU CSB-BP018700HU CSB-MP018700HU CSB-EP018700HU-B |
Recombinant Human Protein kinase C beta type (PRKCB) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRKCB Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018700RA CSB-EP018700RA CSB-BP018700RA CSB-MP018700RA CSB-EP018700RA-B |
Recombinant Rat Protein kinase C beta type (Prkcb) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRKCB Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP018700XBF CSB-EP018700XBF CSB-BP018700XBF CSB-MP018700XBF CSB-EP018700XBF-B |
Recombinant Xenopus tropicalis Protein kinase C beta type (prkcb), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
PRKCB Proteins for Xenopus laevis (African clawed frog)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP759184XBE CSB-EP759184XBE CSB-BP759184XBE CSB-MP759184XBE CSB-EP759184XBE-B |
Recombinant Xenopus laevis Protein kinase C beta type (prkcb), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
