MEFV
Pyrin is a protein in humans that is encoded by MEFV gene. Involved in the regulation of innate immunity and the inflammatory response in response to IFNG/IFN-gamma. Organizes autophagic machinery by serving as a platform for the assembly of ULK1, Beclin 1/BECN1, ATG16L1, and ATG8 family members and recognizes specific autophagy targets, thus coordinating target recognition with assembly of the autophagic apparatus and initiation of autophagy. Acts as an autophagy receptor for the degradation of several inflammasome components, including CASP1, NLRP1 and NLRP3, hence preventing excessive IL1B- and IL18-mediated inflammation.
MEFV Antibodies
MEFV for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA013675LA01HU | MEFV Antibody | Human | ELISA, IHC |
| CSB-PA013675LB01HU | MEFV Antibody, HRP conjugated | Human | ELISA |
| CSB-PA013675LD01HU | MEFV Antibody, Biotin conjugated | Human | ELISA |
MEFV Proteins
MEFV Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP013675HU(A4) CSB-EP013675HU(A4) CSB-BP013675HU(A4) CSB-MP013675HU(A4) CSB-EP013675HU(A4)-B |
Recombinant Human Pyrin (MEFV), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MEFV Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP862375RA CSB-EP862375RA CSB-BP862375RA CSB-MP862375RA CSB-EP862375RA-B |
Recombinant Rat Pyrin (Mefv) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MEFV Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP888319MO CSB-EP888319MO CSB-BP888319MO CSB-MP888319MO CSB-EP888319MO-B |
Recombinant Mouse Pyrin (Mefv), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
