MAGEA4
MAGEA4，即黑色素瘤相關抗原A4，別名MAGE-4、MAGE-41、MAGE-X2等。MAGEA4基因屬于MAGE家族，位于人類的X號染色體上。MAGEA4的作用機制主要涉及其編碼的蛋白質在細胞內的表達，這些蛋白質通常在腫瘤細胞中表達，而在正常組織中表達較低或不表達，尤其是在睪丸等免疫豁免部位。MAGEA4在腫瘤細胞中的表達可能與抑制細胞凋亡和促進腫瘤生長有關。此外，MAGEA4還可以作為免疫治療的靶點，通過激活針對MAGEA4的免疫反應來攻擊腫瘤細胞。MAGEA4在多種腫瘤中表達，包括肺癌、卵巢癌、黑色素瘤等，其表達水平與腫瘤的侵襲性和預后密切相關，MAGEA4的檢測和靶向治療具有重要的生物學意義。
熱銷產品
Recombinant Human Melanoma-associated antigen 4 (MAGEA4) (Active) (CSB-MP013330HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Activity
Measured by its binding ability in a functional ELISA. Immobilized Human MAGEA4 at 2 μg/ml can bind anti-MAGEA4 recombinant antibody, the EC50 is 30.33-43.10 ng/mL.
MAGEA4 Antibody (CSB-PA013330LA01HU)
驗證數據
Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA013330LA01HU at dilution of 1:100
MAGEA4 Antibodies
MAGEA4 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA013330GA01HU | MAGEA4 Antibody | Human | ELISA,IHC |
| CSB-PA059198 | MAGEA4 Antibody | Human | ELISA,IHC |
| CSB-PA179901 | MAGEA4 Antibody | Human | ELISA,IHC |
| CSB-PA013330LA01HU | MAGEA4 Antibody | Human | ELISA, IHC |
| CSB-PA013330LD01HU | MAGEA4 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA013330LC01HU | MAGEA4 Antibody, FITC conjugated | Human | |
| CSB-PA013330LB01HU | MAGEA4 Antibody, HRP conjugated | Human | ELISA |
| CSB-MA013330A0m | MAGEA4 Monoclonal Antibody | Human | ELISA, IHC, FC |
MAGEA4 Proteins
MAGEA4 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP013330HU CSB-EP013330HU CSB-BP013330HU CSB-EP013330HU-B |
Recombinant Human Melanoma-associated antigen 4 (MAGEA4) | Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli |
| CSB-EP013330HU(M) | Recombinant Human Melanoma-associated antigen 4 (MAGEA4) | E.coli |
| CSB-MP013330HU | Recombinant Human Melanoma-associated antigen 4 (MAGEA4) (Active) | Mammalian cell |
| CSB-EP013330HUb0 | Recombinant Human Melanoma-associated antigen 4 (MAGEA4) | E.coli |
