L3T4

L3T4，也被稱為CD4分子，是T淋巴細(xì)胞表面的一種關(guān)鍵受體，它在T細(xì)胞的發(fā)育、激活以及免疫應(yīng)答中起到核心作用。結(jié)構(gòu)上，L3T4由胞外區(qū)、跨膜區(qū)和胞內(nèi)區(qū)組成，能夠特異性地與主要組織相容性復(fù)合體（MHC）II類分子結(jié)合，這對于T細(xì)胞識(shí)別抗原至關(guān)重要。在信號通路上，當(dāng)L3T4與MHC II類分子結(jié)合后，它會(huì)觸發(fā)一系列信號通路的激活，包括酪氨酸激酶途徑、磷脂酶C途徑和鈣離子途徑等，這些通路的激活促進(jìn)T細(xì)胞的增殖、分化和效應(yīng)功能的發(fā)揮。在功能上，L3T4不僅參與T細(xì)胞對“自我”和“非我”的識(shí)別，還在T細(xì)胞分化為輔助性T細(xì)胞（Th細(xì)胞）的過程中發(fā)揮關(guān)鍵作用，并調(diào)節(jié)免疫應(yīng)答的強(qiáng)度和方向，以維持機(jī)體免疫平衡。

熱銷產(chǎn)品

CD4 Recombinant Monoclonal Antibody (CSB-RA004935A0HU)

驗(yàn)證數(shù)據(jù)

Western Blot
Positive WB detected in Jurkat whole cell lysate
All lanes CD4 antibody at 0.8μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 55 KDa
Observed band size: 55 KDa

IHC image of CSB-RA004935A0HU diluted at 1:100 and staining in paraffin-embedded human lymph node tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

IHC image of CSB-RA004935A0HU diluted at 1:100 and staining in paraffin-embedded human spleen tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.

L3T4 Antibody

L3T4 Protein

L3T4 ELISA Kit

L3T4 Antibodies

L3T4 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA004935GA01HU	CD4 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA004935ESR2HU	CD4 Antibody	Human	ELISA, IHC
CSB-PA001453	CD4 Antibody	Human,Mouse	WB, IHC, IF, ELISA
CSB-PA070257	Phospho-CD4 (S433) Antibody	Human,Mouse	IHC, IF, ELISA
CSB-RA004935A0HU	CD4 Recombinant Monoclonal Antibody	Human	ELISA, WB, IHC

L3T4 for H, M, R

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-MA000228	CD4 Monoclonal Antibody	Human,Mouse,Rat	ELISA,IHC

L3T4 Proteins

L3T4 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-CF004935HU	Recombinant Human T-cell surface glycoprotein CD4 (CD4)	in vitro E.coli expression system
CSB-YP004935HU1 CSB-EP004935HU1 CSB-BP004935HU1 CSB-EP004935HU1-B	Recombinant Human T-cell surface glycoprotein CD4 (CD4), partial	Yeast E.coli Baculovirus In Vivo Biotinylation in E.coli