IKBKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon is a protein in humans that is encoded by IKBKE gene. Serine/threonine kinase that plays an essential role in regulating inflammatory responses to viral infection, through the activation of the type I IFN, NF-kappa-B and STAT signaling. Also involved in TNFA and inflammatory cytokines, like Interleukin-1, signaling. Following activation of viral RNA sensors, such as RIG-I-like receptors, associates with DDX3X and phosphorylates interferon regulatory factors (IRFs), IRF3 and IRF7, as well as DDX3X. This activity allows subsequent homodimerization and nuclear translocation of the IRF3 leading to transcriptional activation of pro-inflammatory and antiviral genes including IFNB.
IKBKE Antibodies
IKBKE for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA987228 | IKBKE Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA787742 | IKBKE Antibody | Human,Mouse | ELISA,IHC |
IKBKE Proteins
IKBKE Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP619863HU CSB-EP619863HU CSB-BP619863HU CSB-MP619863HU CSB-EP619863HU-B |
Recombinant Human Inhibitor of nuclear factor kappa-B kinase subunit epsilon (IKBKE) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IKBKE Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP886425MO CSB-EP886425MO CSB-BP886425MO CSB-MP886425MO CSB-EP886425MO-B |
Recombinant Mouse Inhibitor of nuclear factor kappa-B kinase subunit epsilon (Ikbke) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
