HLA-DPB1
HLA class II histocompatibility antigen, DP beta 1 chain is a protein in humans that is encoded by HLA-DPB1 gene. Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and for this reason this antigen presentation pathway is usually referred to as exogenous. As membrane proteins on their way to degradation in lysosomes as part of their normal turn-over are also contained in the endosomal/lysosomal compartments, exogenous antigens must compete with those derived from endogenous components.
HLA-DPB1 Antibodies
HLA-DPB1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA14809A0Rb | HLA-DPB1 Antibody | Human | ELISA, WB, IHC |
HLA-DPB1 Proteins
HLA-DPB1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP361267HU CSB-EP361267HU CSB-BP361267HU CSB-MP361267HU CSB-EP361267HU-B |
Recombinant Human HLA class II histocompatibility antigen, DP beta 1 chain (HLA-DPB1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP361267HU | Recombinant Human HLA class II histocompatibility antigen, DP beta 1 chain (HLA-DPB1), partial | E.coli |
