HCRTR2
HCRTR2，即下丘腦分泌素受體2，別名OX2R、OXR2、ORXR2等 。它是一種G蛋白偶聯受體，主要在大腦皮層、海馬、下丘腦等區域表達 。HCRTR2的作用機制是通過與下丘腦神經肽食欲素A和食欲素B結合，觸發細胞內鈣離子水平的增加，從而調節多種生理功能，包括睡眠-覺醒周期、攝食行為、應激反應等 。HCRTR2的信號通路涉及多種下游分子和途徑，包括G蛋白偶聯受體信號傳導、磷酸酯酶C激活的G蛋白偶聯受體信號傳導等 。生物學意義主要體現在對睡眠-覺醒周期的調節上，HCRTR2的激活能夠促進覺醒狀態，其功能異常與發作性睡病等睡眠障礙的發生發展密切相關 。此外，HCRTR2還在情緒調節、學習記憶等過程中發揮作用 。
熱銷產品
Recombinant Human Orexin receptor type 2 (HCRTR2), partial (CSB-YP010232HU)
驗證數據
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
HCRTR2 Antibody (CSB-PA562577)
驗證數據
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA562577(HCRTR2 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA562577(HCRTR2 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
HCRTR2 Antibodies
HCRTR2 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA949345 | HCRTR2 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA562577 | HCRTR2 Antibody | Human,Mouse,Rat | ELISA,IHC |
HCRTR2 Proteins
HCRTR2 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP010232RA1 CSB-EP010232RA1 CSB-BP010232RA1 CSB-MP010232RA1 CSB-EP010232RA1-B |
Recombinant Rat Orexin receptor type 2 (Hcrtr2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF010232RA | Recombinant Rat Orexin receptor type 2 (Hcrtr2) | in vitro E.coli expression system |
HCRTR2 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP010232MO1 CSB-EP010232MO1 CSB-BP010232MO1 CSB-MP010232MO1 CSB-EP010232MO1-B |
Recombinant Mouse Orexin receptor type 2 (Hcrtr2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF010232MO | Recombinant Mouse Orexin receptor type 2 (Hcrtr2) | in vitro E.coli expression system |
HCRTR2 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP010232HU | Recombinant Human Orexin receptor type 2 (HCRTR2), partial | Yeast |
| CSB-EP010232HU CSB-BP010232HU CSB-MP010232HU CSB-EP010232HU-B |
Recombinant Human Orexin receptor type 2 (HCRTR2), partial | E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-EP010232HU1 | Recombinant Human Orexin receptor type 2 (HCRTR2), partial | E.coli |
HCRTR2 Proteins for Sus scrofa (Pig)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP010232PI CSB-EP010232PI CSB-BP010232PI CSB-MP010232PI CSB-EP010232PI-B |
Recombinant Pig Orexin receptor type 2 (HCRTR2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
HCRTR2 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP880008DO1 CSB-EP880008DO1 CSB-BP880008DO1 CSB-MP880008DO1 CSB-EP880008DO1-B |
Recombinant Dog Orexin receptor type 2 (HCRTR2), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF880008DO | Recombinant Dog Orexin receptor type 2 (HCRTR2) | in vitro E.coli expression system |
