FZD8
FZD8，全稱Frizzled class receptor 8，是一種屬于Frizzled家族的G蛋白偶聯受體，在人類中編碼該蛋白的基因為FZD8。該蛋白常見別名包括FZ-8、hFZ8等。FZD8在多種組織中表達，尤其在神經系統、心血管系統和骨骼系統中具有顯著功能。它通過其細胞外結構域與Wnt配體結合，進而激活下游信號傳導，影響細胞增殖、分化和組織穩態。FZD8與多種疾病相關，如癌癥（結直腸癌、乳腺癌等）和發育障礙。近年來，FZD8成為藥物研發的熱點靶點，研究人員開發了針對FZD8的單克隆抗體和雙特異性抗體，用于阻斷Wnt信號通路，從而抑制腫瘤生長。此外，FZD8也被探索作為治療皮膚創面修復和再生的潛在靶點。
FZD8 Antibodies
FZD8 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA060239 | FZD8 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA617545 | FZD8 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA360153 | FZD8 Antibody | Human,Mouse,Rat | ELISA,IHC |
| CSB-PA880970LA01HU | FZD8 Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA880970LB01HU | FZD8 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA880970LC01HU | FZD8 Antibody, FITC conjugated | Human | |
| CSB-PA880970LD01HU | FZD8 Antibody, Biotin conjugated | Human | ELISA |
FZD8 Proteins
FZD8 Proteins for Xenopus laevis (African clawed frog)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP009111XBE1 CSB-EP009111XBE1 CSB-BP009111XBE1 CSB-MP009111XBE1 CSB-EP009111XBE1-B |
Recombinant Xenopus laevis Frizzled-8 (fzd8), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF009111XBE | Recombinant Xenopus laevis Frizzled-8 (fzd8) | in vitro E.coli expression system |
FZD8 Proteins for Rattus norvegicus (Rat)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP677711RA1 CSB-EP677711RA1 CSB-BP677711RA1 CSB-MP677711RA1 CSB-EP677711RA1-B |
Recombinant Rat Frizzled-8 (Fzd8), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF677711RA | Recombinant Rat Frizzled-8 (Fzd8) | in vitro E.coli expression system |
FZD8 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP726733MO1 CSB-EP726733MO1 CSB-BP726733MO1 CSB-MP726733MO1 CSB-EP726733MO1-B |
Recombinant Mouse Frizzled-8 (Fzd8), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF726733MO | Recombinant Mouse Frizzled-8 (Fzd8) | in vitro E.coli expression system |
FZD8 Proteins for Gallus gallus (Chicken)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP878007CH1 CSB-EP878007CH1 CSB-BP878007CH1 CSB-MP878007CH1 CSB-EP878007CH1-B |
Recombinant Chicken Frizzled-8 (FZD8), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF878007CH | Recombinant Chicken Frizzled-8 (FZD8) | in vitro E.coli expression system |
FZD8 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP880970HU1 CSB-EP880970HU1 CSB-BP880970HU1 CSB-MP880970HU1 CSB-EP880970HU1-B |
Recombinant Human Frizzled-8 (FZD8), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-CF880970HU | Recombinant Human Frizzled-8 (FZD8) | in vitro E.coli expression system |
